ArticleGreen chemistry : an international journal and green chemistry resource : GC2025
Mechanochemical nitration of arenes and alcohols using a bench-stable organic nitrating reagent.
Article in Green chemistry : an international journal and green chemistry resource : GC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Nitrooxylation in Organic Synthesis: From Classical Nitrate Ester Formation to Modern Catalytic Strategies.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- From ball-milling to bead-milling technology: rapid optimization and scale-up of a one-pot Wittig olefination-Diels-Alder reaction sequence using an agitator bead mill.RSC mechanochemistry · 2026Article
- Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity.Angewandte Chemie (International ed. in English) · 2026Review
- Electrophilic and Radical Ability of Organic Nitrating Reagents.The Journal of organic chemistry · 2026Article
- Ketone Oximes as NOThe Journal of organic chemistry · 2026Article
- Environmental impact and sustainability of nanocellulose-based nitrated polymers in propellants.RSC advances · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The installation of a nitro group, essential for synthesizing valuable nitrated compounds, is traditionally associated with harsh reaction conditions, hazardous reagents, and significant environmental concerns. Recent advancements in sustainable nitration methodologies have led to the development of environmentally benign, mild, and non-acidic nitrating reagents, which are often derived from an organic scaffold and can be recycled after the completion of the process. In this study, we demonstrate the practical application of saccharin-derived reagents in mechanochemical electrophilic nitration, utilizing vibratory ball milling under LAG (Liquid-Assisted Grinding) conditions to efficiently functionalize a wide array of alcohols and arenes. This method decreases solvent usage while preserving high selectivity and reactivity, enhancing green chemistry metrics, and fostering greater sustainability in nitration protocols.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.