Evidence map›Paper›PMID 40474899›Full record

ArticleFrontiers in nutrition2025

Low muscle strength and self-reported fatigue in patients on hemodialysis: findings from the SARC-HD study.

Marvery P Duarte, Otávio T Nóbrega, Maryanne Z C Silva, Dario R Mondini, Bruna M Sant'Helena, Daiana C Bundchen, Maristela Bohlke, Angélica N Adamoli, Ricardo M Lima, Antônio Inda-Filho and 5 more

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marvery P DuarteFaculty of Health Sciences, University of Brasilia, Brasília, Brazil.
Otávio T NóbregaFaculty of Health Sciences, University of Brasilia, Brasília, Brazil.
Maryanne Z C SilvaInternal Medicine Department, Botucatu Medical School, São Paulo State University, UNESP, Botucatu, Brazil.
Dario R MondiniLaboratory of Applied Kinesiology, Faculty of Physical Education, Universidade Estadual de Campinas, Campinas, Brazil.
Bruna M Sant'HelenaIELUSC Faculty, Joinville, Brazil.
Daiana C BundchenDepartment of Health Sciences, Federal University of Santa Catarina, Araranguá, Brazil.
Maristela BohlkePostgraduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas, Brazil.
Angélica N AdamoliHospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Ricardo M LimaFaculty of Physical Education, University of Brasilia, Brasília, Brazil.
Antônio Inda-FilhoFaculty of Health Sciences, University of Brasilia, Brasília, Brazil.
João L VianaResearch Center in Sports Sciences, Health Sciences and Human Development, University of Maia, Maia, Portugal.
Barbara P VogtGraduate Program in Health Sciences, Medicine Faculty, Federal University of Uberlandia, Uberlândia, Brazil.
Maycon M ReboredoSchool of Medicine, Federal University of Juiz de Fora, Juiz de Fora, Brazil.
Heitor S RibeiroFaculty of Health Sciences, University of Brasilia, Brasília, Brazil.
SARC-HD Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Whether low muscle strength contributes to fatigue remains poorly understood. We investigated the association between dynapenia and self-reported fatigue in patients on hemodialysis. Methods: A cross-sectional analysis of the multicenter SARC-HD study in 19 dialysis units across Brazil. Muscle strength was evaluated by handgrip strength (HGS) and five times sit-to-stand (STS-5). Low muscle strength (i.e., dynapenia) was defined based on the revised EWGSOP. Patients were stratified into four dynapenia phenotypes (i) no dynapenia; (ii) low HGS; (iii) low STS-5; and (iv) severe dynapenia (low HGS and STS-5). From the validated 36-item short-form health survey (SF-36) question about tiredness, patients self-reported their frequency of fatigue as (i) Results: Among 841 patients (58 ± 15 years, 38% female, and 49% Black), the prevalences of dynapenia by low HGS, low STS-5, and severe dynapenia were 13.9, 18.8, and 12.1%, respectively. Frequency of fatigue, self-reported as " Conclusion: Patients on hemodialysis with low muscle strength were more likely to self-report a higher frequency of fatigue, independently of the dynapenia phenotype. This highlights the importance of recognizing low muscle strength as a potential contributor to fatigue in this population.

Indexed as

dialysisfatiguemuscle weaknesssarcopeniatiredness

Identifiers

PMID40474899
PMCPMC12137102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.