Evidence map›Paper›PMID 40474710›Full record

ArticlePathologica2025

Laura Libera, Nora Sahnane, Mario Turri-Zanoni, Fabiana Pettenon, Deborah Marchiori, Paolo Battaglia, Alberto Daniele Arosio, Daniela Furlan, Maurizio Bignami, Paolo Castelnuovo and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Laura LiberaUnit of Pathology, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy.
Nora SahnaneUnit of Anatomic Pathology, Azienda Socio Sanitaria Territoriale (ASST) dei Sette Laghi, Varese, Italy.
Mario Turri-ZanoniDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, and ASST Sette-Laghi, Varese, Italy.
Fabiana PettenonUnit of Anatomic Pathology, Azienda Socio Sanitaria Territoriale (ASST) dei Sette Laghi, Varese, Italy.
Deborah MarchioriUnit of Anatomic Pathology, Azienda Socio Sanitaria Territoriale (ASST) dei Sette Laghi, Varese, Italy.
Paolo BattagliaDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, and ASST Sette-Laghi, Varese, Italy.
Alberto Daniele ArosioDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, and ASST Sette-Laghi, Varese, Italy.
Daniela FurlanUnit of Pathology, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy.
Maurizio BignamiDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, and ASST Sette-Laghi, Varese, Italy.
Paolo CastelnuovoDivision of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, and ASST Sette-Laghi, Varese, Italy.
Fausto SessaUnit of Pathology, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy.
Carla FaccoUnit of Anatomic Pathology, Azienda Socio Sanitaria Territoriale (ASST) dei Sette Laghi, Varese, Italy.
Michele CeratiUnit of Anatomic Pathology, Azienda Socio Sanitaria Territoriale (ASST) dei Sette Laghi, Varese, Italy.
Stefano La RosaUnit of Pathology, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sino-nasal mucosal melanoma (SN-MM) is an aggressive and rare form of melanoma arising from mucosal melanocytes with pathogenesis unrelated to sun exposure. Conversely to cutaneous melanoma (CM), the molecular bases underling SN-MM development and progression are unclear, and no molecular predictive markers have been identified yet. To better define the molecular landscape of SN-MM, a retrospective series of 37 SN-MMs from 31 patients was analysed for both somatic mutations and cytogenetic alterations. The somatic mutation analysis identified the presence of a driver gene pathogenic variant in 54% of cases. In detail, mutually exclusive

Indexed as

DNA Copy Number VariationsGTP PhosphohydrolasesMelanomaMembrane ProteinsParanasal Sinus NeoplasmsProto-Oncogene Proteins p21(ras)AdultAgedAged, 80 and overBiomarkers, TumorFemaleHumansMaleMiddle AgedMutationPrognosisBiomarkers, TumorGTP PhosphohydrolasesKRAS protein, humanMembrane ProteinsNRAS protein, humanProto-Oncogene Proteins p21(ras)copy number alterationsmolecular analysisSinonasal melanoma

Identifiers

PMID40474710
PMCPMC12142291

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.