Evidence map›Paper›PMID 40474511›Full record

ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2025

Influence of Thickener and Mineral Supplementation of Bleaching Gels on Enamel Demineralization.

Adrielle Caroline Moreira Andrade, Allegra Comba, Nicola Scotti, Leila Es Sebar, Carlos Rocha Gomes Torres

Abstract read
In one paragraph

Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. High-Concentration Hydrogen Peroxide Gels Containing Calcium Polyphosphate Associated With Violet Led Light: Bleaching Efficacy and Effects on Enamel Properties.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Article
  3. Article
  4. Review
  5. Influence of Thickener and Mineral Supplementation of Bleaching Gels on Enamel Demineralization.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adrielle Caroline Moreira AndradeDepartment of Restorative Dentistry, Institute of Science and Technology, Sao Paulo State University - UNESP, Sao Jose dos Campos, Brazil.ORCID 0000-0003-0779-5152
Allegra CombaDepartment of Surgical Sciences, University of Turin, Dental School, Endodontics and Operative Dentistry, Turin, Italy.ORCID 0000-0002-4057-1428
Nicola ScottiDepartment of Surgical Sciences, University of Turin, Dental School, Endodontics and Operative Dentistry, Turin, Italy.ORCID 0000-0001-7380-1675
Leila Es SebarPolitecnico di Torino, Corso Duca degli Abruzzi, Turin, Italy.ORCID 0000-0001-6463-9311
Carlos Rocha Gomes TorresDepartment of Restorative Dentistry, Institute of Science and Technology, Sao Paulo State University - UNESP, Sao Jose dos Campos, Brazil.ORCID 0000-0002-9485-5514

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 303781/2021-1São Paulo Research Foundation (FAPESP) #2022/04270-1
6 · The paper itself

Abstract

objectiveThis study evaluated the effect of the type of thickener and mineral supplementation of bleaching gels on enamel demineralization. MATERIALS AND

methodsEnamel specimens were divided into five groups according to the type of thickener: CA-Carbopol, AE-Aerosil 200, PO-Poloxamer 407, GG-Guar gum, and HEC-Hydroxyethyl cellulose. Each group was subdivided into three subgroups according to the level of mineral supplementation: none, saturation concentration, and maximum addition. The microhardness (KHN), surface roughness (Ra), color change (ΔE00), and mineral content (DD) were measured before and after the treatment, and the changes were calculated. The data was analyzed with two-way ANOVA and Tukey's test.

resultsANOVA showed significant differences among the groups (p < 0.05). The results of the Tukey test were: %KHN-HEC>GG>CA>PO>AE. %Ra-CA>HEC>PO>GG>AE. DE00-AE>GG>PO>HEC. %DD-HEC>PO>GG>CA>AE. The supplementation reduced the means of %KHN, %Ra, and %DD, without affecting the DE00. The effect of the supplementation level was not statistically significant.

conclusionIt was concluded that the type of thickener and the use of mineral supplementation significantly influenced the deleterious effects on the enamel.

Indexed as

Dental EnamelMineralsTooth BleachingTooth Bleaching AgentsTooth DemineralizationGelsHumansSurface PropertiesGelsMineralsTooth Bleaching Agentscalciumdemineralizationdental enamelphosphorusthickenertooth bleaching

Identifiers

PMID40474511
PMCPMC12315608

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.