ArticleBiophysical journal2025
Effectiveness of outer hair cells as cochlear amplifier: In simple model systems.
Article in Biophysical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Dynamical and Stochastic Analysis of a Piezoelectric Neuron Model for Intelligent Sensing Applications.Sensors (Basel, Switzerland) · 2026Article
- Coupled oscillator mechanism extends the amplifying effect of outer hair cells to high frequencies.Scientific reports · 2025Article
Corrections and comments
- Erratum issued
- Update of
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cochlear outer hair cells (OHCs) have two mechanosensitive elements: the hair bundle (HB) with mechanotrasducer channels and the piezoelectric lateral wall of the cell body. The present report examines how these elements interact with each other by incorporating OHCs into the simplest local cochlear models. In the frequency range, typically above 1 kHz, where capacitive conductance is greater than the ionic conductance, HB conductance drives the piezoelectric cell body and amplified oscillation by countering viscous drag, whereas the cell body increases its stiffness owing to strain-induced polarization, elevating the resonance frequency. Since HB sensitivity is essential for amplification, the resonance is not pure piezoelectric but semi-piezoelectric. In the lower-frequency range, typically lower than 100 Hz, strain-induced polarization contributes to drag, and the HB sensitivity increases cell body stiffness.
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