Evidence map›Paper›PMID 40474380›Full record

ArticleJournal of applied clinical medical physics2025

Comprehensive end-to-end dosimetry audit for stereotactic body radiotherapy in spine, lung, and soft tissue.

Maddison Shaw, Andrew Alves, Jessica Lye, Joerg Lehmann, Fayz Kadeer, Sabeena Beveridge, Nicholas Hardcastle, Moshi Geso, Rhonda Brown

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maddison ShawAustralian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, Melbourne, Australia.
Andrew AlvesAustralian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, Melbourne, Australia.
Jessica LyeAustralian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, Melbourne, Australia.
Joerg LehmannDepartment of Radiation Oncology, Calvary Mater Newcastle, Newcastle, Australia.
Fayz KadeerAustralian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, Melbourne, Australia.
Sabeena BeveridgeAustralian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, Melbourne, Australia.
Nicholas HardcastleDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, Australia.
Moshi GesoSchool of Health and Biomedical Sciences, RMIT University, Melbourne, Australia.
Rhonda BrownAustralian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, Melbourne, Australia.

Funding

Australian Government Research Training Program
6 · The paper itself

Abstract

purposeTo create and conduct a comprehensive onsite end-to-end dosimetry audit to assess treatment accuracy of spine, lung, and soft tissue Stereotactic Body Radiotherapy (SBRT) across Australian and New Zealand (ANZ) radiotherapy centers.

methodsThe Australian Clinical Dosimetry Service (ACDS) anthropomorphic thorax phantom underwent a CT scan, planning, and treatment delivery according to local techniques at 128 facilities. Target volumes and dose constraints for spine, lung, and soft tissue were defined by the ACDS. Each plan was measured using Gafchromic EBT3 film and PTW 60019 microDiamond detector. A total of 782 plans were measured on 159 treatment machines of various classes and vendors. Audit results with the measured dose calculated as dose-to-medium, in medium (D

resultsThe overall audit pass rate was 96% (271/281 plans) for the soft tissue case, 90% (215/238) for the spine, and 90% (236/263) for the lung. The average gamma pass rate for 5%/2mm criteria was 98.7% (soft tissue), 96.5% (spine), and 96.5% (lung). The average point dose difference was -1.0% (± 2.3%), 0.1% (± 3.8%), and -0.3% (± 3.2%) for the soft tissue, spine, and lung cases, respectively. The most common failure modes were in-target dose differences (41.6%) and Image Guided Radiation Therapy (IGRT) mismatches (36.7%).

conclusionsHigh pass rates were seen for soft tissue, spine, and lung SBRT, indicating safe implementation of practice in the ANZ region. The modes of failure were assessed for suboptimal results, with the most frequent error due to IGRT mismatches, followed by dose differences in field, either underdosing or overdosing.

Indexed as

Lung NeoplasmsMedical AuditPhantoms, ImagingRadiometryRadiosurgeryRadiotherapy Planning, Computer-AssistedSoft Tissue NeoplasmsSpinal NeoplasmsHumansOrgans at RiskQuality Assurance, Health CareRadiotherapy DosageRadiotherapy, Intensity-Modulateddose to mediumdosimetry auditmulticentre studyQASABRSBRT

Identifiers

PMID40474380
PMCPMC12256566

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.