ArticleClinical oral implants research2025
Bi-Layered Biphasic Calcium Phosphate Bone Substitute to Improve Bone Formation in Lateral Jaw Defects Applying the Principle of Guided Bone Regeneration (GBR)-A Pre-Clinical Randomized Controlled Study.
Article in Clinical oral implants research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Engineered Xenogeneic Bone Scaffold with IL-10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
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4 authors.
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Abstract
aimTo evaluate the application of a synthetic bi-layered biphasic calcium-phosphate (BBCP) bone substitute for its capacity for new bone formation in Guided Bone Regeneration (GBR) in an acute-defect model in Beagle dogs. MATERIAL AND
methodsStandardized bone defects were created following the extraction of the maxillary
resultsAll biomaterials resulted in increased volume of the augmented bone compared to the negative control. The augmented ridge volume developed to a greater extent in the tested area and in the combination of the tested bone substitute and the DBBM compared to the positive control alone (DBBM). A significant increment in a mineralized tissue and bone-biomaterial contact was observed between the test groups and the positive control.
conclusionsThe synthetic BBCP appeared to result in greater bone formation volumes than the positive control (DBBM) and resulted in less contact with soft tissue. Hence, the tested material appeared to be at least as effective as the applied standard for lateral bone augmentation (DBBM).
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