ArticlePediatric transplantation2025
Medication Adherence Status and Influencing Factors in Adolescent Kidney Transplant Recipients.
Article in Pediatric transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Psychosocial challenges faced by children who had a solid organ transplant: adherence, transition, and posttraumatic stress.Current opinion in organ transplantation · 2026Review
- Medication self-management during the developmental transition of responsibility among Chinese adolescent liver transplant recipients: a qualitative descriptive study.European journal of pediatrics · 2026Article
- Kidney transplantation beyond immunosuppression: shifting the focus from graft survival to patient health.Frontiers in immunology · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundThis study investigated medication adherence and related factors in adolescent kidney transplant recipients receiving immunosuppressive drugs.
methodsBetween February and October 2023, 115 adolescent kidney transplant recipients were selected through convenience sampling from follow-up centers in four Chinese tertiary hospitals. The study assessed medication adherence and influencing factors via a general information questionnaire, an adherence assessment scale, a medication belief scale, and an overall happiness scale.
resultsThe average medication adherence score was 4.98 ± 2.32 points, with 60.08% (76/115) showing poor adherence. Five of these patients experienced graft failure, resulting in a 6.5% failure rate. No cases of graft failure occurred in those with excellent compliance. Univariate analysis revealed no significant differences in adherence based on sex, age, income, or education (p > 0.05). However, statistically significant differences in medication adherence were observed based on rejection reactions and infections (p < 0.01). Pearson's correlation analysis revealed that higher perceived medication necessity and overall happiness scores were correlated with better adherence (p < 0.05). Linear regression revealed that post-transplant rejection, infections, perceived medication necessity, and overall happiness significantly impacted adherence (p < 0.05).
conclusionThe high prevalence of poor medication adherence among adolescent kidney transplant recipients highlights the importance for healthcare professionals to focus on monitoring significant post-transplant complications, improving recipients' understanding of the necessity of their medications, and evaluating their overall psychological well-being. Introducing an effective early warning system during home follow-up periods can enable timely interventions to improve medication adherence.
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