Evidence map›Paper›PMID 40474281›Full record

ArticleReproductive health2025

Epidemiological trends in abortion and miscarriage between 1990 and 2019.

Yadi Wang, Yujie Tang, Guoshuai Wang, Ran Wei, Lu Liu, Chao Lu

Abstract read
In one paragraph

Article in Reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. The Decline of Abortion in Spain Over the Last Decade.Perspectives on sexual and reproductive health · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yadi Wang *Department of Reproductive Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong Province, 261000, P.R. China.
Yujie Tang *Department of Reproductive Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong Province, 261000, P.R. China.
Guoshuai Wang *Department of Reproductive Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong Province, 261000, P.R. China.
Ran WeiDepartment of Reproductive Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong Province, 261000, P.R. China.
Lu LiuDepartment of Reproductive Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong Province, 261000, P.R. China.
Chao LuDepartment of Reproductive Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong Province, 261000, P.R. China. vincentslu@163.com.

Funding

Foundation of Weifang Yuandu Scholar No. ydxz2023021Science and technology support plan for youth innovation in universities of Shandong Province 2021KJ107
6 · The paper itself

Abstract

backgroundAbortion and miscarriage both lead to pregnancy loss, with miscarriage occurring spontaneously and abortion referring to the intentional ending of pregnancy. In this context, unsafe remains a major threat to reproductive health. To inform public health strategies and improve maternal health outcomes, it is essential to monitor the epidemiological data associated with abortion and miscarriage. In this study, we utilized data from the Global Burden of Disease Study (GBD) 2019 to comprehensively assess the global burden of abortion and miscarriage from 1990 to 2019.

methodsThe available data were stratified by year, age, and social development index (SDI) at the global, regional, and country levels from the GBD 2019 database. Furthermore, we employed estimated annual percentage changes (EAPCs) to assess the age-standardized rates of abortion and miscarriage. Additionally, linear regression analysis was conducted to examine the relationship between abortion rates and SDI values.

resultsThe global incidence of abortion and miscarriage decreased from 49,637,961 in 1990 to 42,385,827 in 2019. The number of deaths dropped significantly from 59,475 to 19,565, while disability-adjusted life years (DALYs) decreased from 3,449,222 to 1,130,038 over the same period. Despite this overall decline, the disease burden remains substantial in some regions. The low-SDI had the highest age-standardized incidence rate (ASIR), reaching 1,983.8 per 100,000. At the national level, Ethiopia recorded the highest ASIR at 3,839.06 per 100,000 in 2019, followed by Bolivia at 3,524.9 per 100,000. Among 204 countries and territories, Chad (17.59 per 100,000) and Niger (14.02 per 100,000) had the highest age-standardized death rates (ASDR) in 2019. Among the 21 GBD regions, Eastern Sub-Saharan Africa had the highest DALY rate in 2019, amounting to 208.42 per 100,000. Globally, a high incidence cases (13,341,611) was recorded for young women aged 20 to 29 years, meanwhile deaths (3,239) was higher in women aged 35 to 44 years.

conclusionsBy identifying key risk factors and high-burden areas, we hope to provide a usable theoretical basis for policymakers and healthcare professionals to develop targeted interventions that improve reproductive health outcomes.

Indexed as

Abortion, InducedAbortion, SpontaneousAdolescentAdultDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseGlobal HealthHumansIncidencePregnancyYoung AdultAbortionDisability-adjusted life-yearsGlobal burden of diseaseSocial development index

Identifiers

PMID40474281
PMCPMC12143105

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.