ReviewRadiation oncology (London, England)2025
Radiation-induced cardiac substructure damage and dose constraints: a review.
Review in Radiation oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Left atrial and left ventricular radiation exposure predict long-term cardiovascular events after breast cancer radiotherapy.Clinical and translational radiation oncology · 2027Article
- Radiotherapy-Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments.MedComm · 2026Review
- Review
- Dosimetric comparison of three different radiotherapy regimens for bilateral breast cancer.Biomedical engineering online · 2026Article
- Comparative analysis of artificial intelligence-based contouring of cardiac substructures on computed tomography scans for radiation therapy.Physics and imaging in radiation oncology · 2026Article
- Ionizing radiation: molecular mechanisms, biological effects, and therapeutic targets.Molecular biomedicine · 2026Review
- Beyond mean heart dose: quantitative impact of sub-structure spatial dosimetrics on subclinical myocardial strain in thoracic radiotherapy.Frontiers in cardiovascular medicine · 2026Article
- Beyond mean heart dose: differentiated electrocardiographic manifestations and dosimetric mechanisms of cardiac injury in left-sided versus right-sided breast cancer after intensity-modulated radiotherapy.Frontiers in oncology · 2026Article
- Metabolic reprogramming in radiation-induced heart disease: the emerging role of PET imaging.Frontiers in cardiovascular medicine · 2026Review
- Impact of Heart Dose on Survival in Palliative Radiotherapy for Bone Metastases: Propensity Score-matched Analysis.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The field of radiation-induced cardiac damage (RIHD) is garnering increasing attention. The application of advanced radiotherapy reduces the cardiac radiation dose. Still, challenges remain in the uneven dose distribution, the different sensitivity among cardiac substructures (CSs), and the delineation of target areas within these substructures. This article encompasses cardiac substructures, including atria and ventricles, coronary arteries, pulmonary vasculars and superior vena cava (SVC), cardiac conduction system, heart valves and heart base. This review will provide better understanding of RIHD as it firstly summarizes dose limitation of CSs, as well as the risk of cardiac toxicities and its impact on survival following the comprehensive search.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.