Evidence map›Paper›PMID 40474217›Full record

Trial reportReproductive health2025

The impact of the SKILLZ intervention on sexual and reproductive health empowerment among Zambian adolescent girls and young women: results of a cluster randomized controlled trial.

Lila A Sheira, Chama Mulubwa, Calvin Chiu, Jenala Chipungu, Chelsea Coakley, Helene Smith, Ushma D Upadhyay, Chansa Chilambe, Besa Chibwe, Jake M Pry and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04429061 (Reaching 90 90 90 in Adolescents in Zambia), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04429061 nacompletednot on this map

Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2020 to 2023Enrolled2,153ConditionsHIV Infections, Pregnancy Related, STI, Mental Health Wellness 1ArmsSKILLZ-Girl curriculum
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lila A SheiraInstitute for Health & Aging, School of Nursing, University of California, San Francisco, USA. Lila.sheira@ucsf.edu.
Chama MulubwaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Calvin ChiuInstitute for Health & Aging, School of Nursing, University of California, San Francisco, USA.
Jenala ChipunguCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Chelsea CoakleyDesmond Tutu HIV Centre, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Helene SmithSchool of Population Health, University of New South Wales, Sydney, Australia.
Ushma D UpadhyayDepartment of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco, USA.
Chansa ChilambeCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Besa ChibweCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Jake M PryCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Boyd MkandawireGrassroot Soccer Zambia, Lusaka, Zambia.
Maggie MusondaGrassroot Soccer Zambia, Lusaka, Zambia.
Carolyn Bolton MooreCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Jenny LiuInstitute for Health & Aging, School of Nursing, University of California, San Francisco, USA.

Funding

Reaching 90 90 90 in Adolescents in Zambia: Using all our SKILLZR01MH116789 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BOLTON MOORE, CAROLYN, LIU, JENNY XIN · 2018 to 2022
$2.3M
NIMH NIH HHS R01 MH116789NIMH NIH HHS R01MH116789
6 · The paper itself

Abstract

backgroundZambian adolescent girls and young women (AGYW, age 15–24) experience a disproportionate burden of HIV and unintended pregnancy. Sports-based interventions, which affect sexual health behaviors via improving sexual and reproductive empowerment, may be an innovative and effective approach for promoting HIV and unintended pregnancy prevention. We sought to evaluate the impact of a peer-led, sports-based intervention on sexual and reproductive empowerment among in-school Zambian adolescent girls and young women.

methodsData come from the ‘SKILLZ’ study, a cluster randomized controlled trial evaluating the impact of a peer-led, sports-based health education program. Sexual and reproductive empowerment, a secondary outcome of SKILLZ, was measured via the 23-item Sexual and Reproductive Empowerment for adolescents and young adults scale (range 0–92, higher = more sexual and reproductive empowerment) three times over approximately 24 months. We conducted a difference-in-differences analysis to evaluate intervention impact over time.

resultsThe study enrolled 2,153 AGYW (1134 intervention; 1019 control) across 46 secondary schools in Lusaka. Median age at baseline was 17; participants were largely unmarried (96%), with 20% reporting any sexual activity. By endline, nearly 40% reported being sexually active. Between baseline and midline, attending an intervention school was associated with a 6.21-point increase in overall score calculated using the imputed sample (standard error [SE]: 0.75, p < 0.001) compared to being in a control school (6.75% change). At endline, being in an intervention school was associated with a 5.12-point increase in the Sexual and Reproductive Empowerment overall score (SE: 0.71, p < 0.001; 5.57% change)). Among sexually active AGYW, being in an intervention school was associated with a 7.78-point (SE: 1.17, p < 0.001) and 4.64-point increase (SE: 0.93, p < 0.001) from the baseline to the midline and endline rounds, respectively (8.46% and 5.04% change, respectively).

conclusionThe intervention moderately impacted Sexual and Reproductive Empowerment scores; results were magnified among sexually active AGYW. Given adolescence is a critical period for sexuality and gender programming, as well as for sexual debut, empowerment interventions at schools may support downstream sexual health behaviors that will impact the life-course of AGYW.

trial registrationThis study was registered in ClinicalTrials.gov (NCT04429061) on March 17th, 2020.

Indexed as

EmpowermentHealth EducationReproductive HealthSexual BehaviorSexual HealthAdolescentFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansPregnancyYoung AdultZambiaAdolescent healthEmpowermentSexual and reproductive healthUnintended pregnancyZambia

Identifiers

PMID40474217
PMCPMC12142864

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.