ArticleBMC surgery2025
Efficacy of high-dose estrogen and progesterone sequential assisted hysteroscopic cold knife separation versus hysteroscopic cold knife separation alone in the treatment of infertility or amenorrhea caused by severe intrauterine adhesion: a retrospective cohort study.
Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Asherman Syndrome in Mexican Women: Clinical Characteristics, Management, and Outcomes at a Tertiary Hospital.Journal of clinical medicine · 2026Article
- Unintended pregnancy with retained intrauterine balloon after hysteroscopic adhesiolysis: a case report.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo investigate the effect of high-dose estrogen and progesterone sequential assisted hysteroscopic cold knife separation surgery on the recovery of uterine cavity morphology in patients with severe intrauterine adhesions (IUA).
methodsThis was a retrospective cohort study. A total of 200 patients with severe IUA were selected as the research objects, and the selected period was from August 2020 to August 2023. According to different treatment methods, patients were divided into the surgical group (hysteroscopic cold knife separation surgery, n = 82) and the combined group (high-dose estrogen and progesterone sequential assisted hysteroscopic cold knife separation surgery, n = 118). The clinical effects and menstrual blood loss map (PBAC) scores were compared between the two groups. The uterine cavity shape recovery was observed before treatment and 2 months after treatment. Multivariate Logistic regression analysis was used to analyze the influencing factors.
resultsCompared with 79.27% in the surgical group, the effective rate of the combined group was 94.07%, which was higher (χ
conclusionIn the treatment of severe IUA, high-dose estrogen and progesterone sequential assisted hysteroscopic cold knife separation surgery can promote the recovery of uterine cavity morphology, reduce the incidence of postoperative IUA, and improve the postoperative pregnancy rate of patients. This was a retrospective study with limitations such as single sample and short follow-up time. Prospective studies with extended follow-up are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.