ArticleBMC neurology2025
Construction and evaluation of an aspirin resistance risk prediction model for ischemic stroke.
Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- The Interconnected World of Coagulation Factors, Platelets and Plasminogen: A Novel Perspective on Biosynthetic Regulation.Life (Basel, Switzerland) · 2025Review
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5 authors.
Funding
Abstract
backgroundAspirin has become the drug of choice for the prevention and treatment of ischemic stroke (IS), but approximately a quarter of patients may be resistant to its effects and have an increased risk of recurrent ischemic events while also developing aspirin resistance. This study aimed to build a risk prediction model for aspirin resistance (AR) in IS patients, predicts the likelihood of IS patients developing AR.
methodsThe retrospective research study included the clinical data of patients with ischemic stroke were retrospectively collected from January 2021 to January 2023 at the Affiliated Hospital of Beihua University in the Jilin Province. Univariate and logistic regression analyses were used to construct a risk prediction model. The Hosmer-Lemeshow χ
resultsA total of 285 patients participated in this study, of whom 206 did not have AR, while 79 had AR. Seven risk factors were included in the prediction model. Sex (female), age (≥ 60 years), smoking, diabetes mellitus (DM), hyperlipidemia (HLP), platelets (PLT), > 350 × 10
conclusionsGender (female), age, smoking, DM, HLP, PLT and HbA1c are independent risk factors for AR in IS. The AR risk prediction model for IS demonstrates strong predictive and discriminative performance, enabling precise identification of high-risk patients.
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