Evidence map›Paper›PMID 40474039›Full record

ArticleWorld journal of microbiology & biotechnology2025

Rapid detection of brucellosis by a two-signal vertical flow immunoassay based on sea urchin-like gold nanoparticles.

Chao Tong, Tongtong Zhang, Zhenghong Xu, Min Zhang, Zhihua Xu, Yu Ma, Zhihan Niu, Feng Shi

Abstract read
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In one paragraph

Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chao Tong *The Friendship Hospital of Ili Kazakh Autonomous Prefecture, Yining, 835099, China.
Tongtong Zhang *Department of Biotechnology, College of Life Sciences, Shihezi University, Shihezi, 832003, China.
Zhenghong XuDepartment of Biotechnology, College of Life Sciences, Shihezi University, Shihezi, 832003, China.
Min ZhangDepartment of Biotechnology, College of Life Sciences, Shihezi University, Shihezi, 832003, China.
Zhihua XuDepartment of Biotechnology, College of Life Sciences, Shihezi University, Shihezi, 832003, China.
Yu MaDepartment of Biotechnology, College of Life Sciences, Shihezi University, Shihezi, 832003, China.
Zhihan NiuDepartment of Biotechnology, College of Life Sciences, Shihezi University, Shihezi, 832003, China.
Feng ShiDepartment of Biotechnology, College of Life Sciences, Shihezi University, Shihezi, 832003, China. shifeng2314@yeah.net.

Funding

Autonomous Prefecture Science and Technology Program YJC2024A12Division I Science and Technology Program Projects 2024YL04
6 · The paper itself

Abstract

Brucellosis, a chronic zoonotic disease caused by Brucella, poses a significant threat to global public health and safety. While vertical flow immunoassay (VFI) is an effective tool for detecting brucellosis, its low sensitivity and poor quantitative ability significantly limit its application in brucellosis detection. Therefore, in this study, a dual-mode signal output technique was designed for rapid detection of brucellosis using the photothermal properties of sea urchin-like gold particles (ULGNs). ULGNs were prepared using the hydroquinone reduction method, and their localized surface plasmon resonance (LSPR) peaks could be easily tuned to the near-infrared (NIR) range by controlling the surface spikes. Subsequently, the ULGNs were detected using a Staphylococcus aureus protein A(SPA) probe coupled to the ULGNs. The colorimetric signal, observed by the naked eye, could show the results within 10 min, and its minimum detection limit was 2 IU mL

Indexed as

BrucellosisGoldMetal NanoparticlesAnimalsBrucellaColorimetryHumansImmunoassayLimit of DetectionSea UrchinsSensitivity and SpecificityStaphylococcal Protein ASurface Plasmon ResonanceGoldStaphylococcal Protein ABrucellosisColorimetric detectionDual-mode detectionPhotothermal detectionSea urchin-like gold nanoparticlesVertical flow immunoassay

Identifiers

PMID40474039

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.