Evidence map›Paper›PMID 40474020›Full record

ArticleUpdates in surgery2025

Endoscopic management of subglottic stenosis with innovative transcordal stent.

Leonardo Teodonio, Beatrice Trabalza Marinucci, Valentina Peritore, Francesco Cassiano, Amir Hanna, Giacomo Argento, Gaetana Messina, Beatrice Leonardi, Alfonso Fiorelli, Claudio Andreetti

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Article in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leonardo TeodonioDepartment of Thoracic Surgery, Sant'Andrea Hospital-Sapienza University, Via Di Grottarossa 1035-1039, 00189, Rome, Italy.
Beatrice Trabalza MarinucciDepartment of Thoracic Surgery, Sant'Andrea Hospital-Sapienza University, Via Di Grottarossa 1035-1039, 00189, Rome, Italy.
Valentina PeritoreDepartment of Thoracic Surgery, Sant'Andrea Hospital-Sapienza University, Via Di Grottarossa 1035-1039, 00189, Rome, Italy.
Francesco CassianoDepartment of Thoracic Surgery, Centre Chirurgical Marie Lannelongue, Paris, France.
Amir HannaDepartment of Thoracic Surgery, Centre Chirurgical Marie Lannelongue, Paris, France.
Giacomo ArgentoDepartment of Thoracic Surgery, Sant'Andrea Hospital-Sapienza University, Via Di Grottarossa 1035-1039, 00189, Rome, Italy.
Gaetana MessinaDepartment of Thoracic Surgery, Policlinico Vanvitelli-University of Campania, Naples, Italy.
Beatrice LeonardiDepartment of Thoracic Surgery, Policlinico Vanvitelli-University of Campania, Naples, Italy.
Alfonso FiorelliDepartment of Thoracic Surgery, Policlinico Vanvitelli-University of Campania, Naples, Italy.
Claudio AndreettiDepartment of Thoracic Surgery, Sant'Andrea Hospital-Sapienza University, Via Di Grottarossa 1035-1039, 00189, Rome, Italy. claudio.andreetti@uniroma1.it.ORCID http://orcid.org/0000-0003-0327-0527

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-stage tracheal resection and anastomosis represents the gold standard for benign subglottic stenosis' management. Nevertheless, also considering the complexity of the surgical procedure, some patients are considered unfit for tracheal surgery (stenosis involving vocal cords, comorbidities, and relapse after surgery). Until now, the only alternative was tracheostomy which represents the only real alternative to secure the patency of the airway. Thanks to the creation of "transcordal stents", patients considered unfit for surgery have a valid alternative to tracheostomy and the conformation of the stent reduces the risk of stent migration, preserving airway patency, swallowing, and phonation. This study aims to evaluate the use of a new custom-made transcordal stent, comparing its safeness with traditional transcordal stent. Between 2017 and 2021, 28 consecutive patients underwent transcordal stenting for benign tracheal stenosis in 3 centers. Patients were divided into 2 groups: 16 treated with the new custom-made stent (Group 1) and 12 treated with conventional stents (Group 2). Intra-, post-operative complications, swallowing capacity, quality of voice, granulation tissue, stent migration, and quality of life (QoL) were compared between the two groups. Group 2 showed reduced swallowing capacity (p = 0.0001), higher rate of stent migration (p = 0.0003), higher rate of granulation tissue (p = 0.0044), and higher rate of stent replacement (p = 0.0001). Voice reduction was not significantly different between the two groups. QoL was better in Group 1. Despite this represent the largest study analyzing transcordal stenting as definitive treatment of subglottic stenosis in patients unfit for surgery, results could not draw definitive conclusions because of the small number of patients, the lack of randomization, and the small follow-up. Nevertheless, the use of the new custom-made transcordal stent could be considered safe and effective, guaranteeing stable results with low rate of long-term complications and better QoL compared to the traditional stents.

Indexed as

EndoscopyLaryngostenosisStentsAdultAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsProsthesis DesignQuality of LifeTreatment OutcomeBenignEndoscopic treatmentStenosisStentSubglotticTracheal surgery

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.