Evidence map›Paper›PMID 40474001›Full record

ArticleClinical and experimental nephrology2025

Whole slide imaging for rapid treatment decision-making and education in renal pathology.

Emiko Otsuka, Mineaki Kitamura, Kiyokazu Tsuji, Kenta Torigoe, Ayuko Yamashita, Nozomi Ueki, Yuki Matsuoka, Takahiro Takazono, Noriho Sakamoto, Kumiko Muta and 4 more

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Article in Clinical and experimental nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Emiko OtsukaDepartment of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Mineaki KitamuraDepartment of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. minekitamura@nagasaki-u.ac.jp.ORCID http://orcid.org/0000-0002-0003-8645
Kiyokazu TsujiDepartment of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Kenta TorigoeDepartment of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Ayuko YamashitaDepartment of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Nozomi UekiDepartment of Tumor and Diagnostic Pathology, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Yuki MatsuokaDepartment of Pathology, Nagasaki University Hospital, Nagasaki, Japan.
Takahiro TakazonoDepartment of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Noriho SakamotoDepartment of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Kumiko MutaDepartment of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Hisayuki HamadaMedical Education Department Center, Nagasaki University Hospital, Nagasaki, Japan.
Masahiro NakashimaDepartment of Tumor and Diagnostic Pathology, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Hiroshi MukaeDepartment of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Tomoya NishinoDepartment of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhole slide imaging (WSI) is digital imaging technique that involves scanning glass slides. Although WSI is widely used in pathological diagnosis and education, its impact on nephrology education remains unknown. We clarified the usefulness of WSI in rapid treatment decision-making and education in renal pathology.

methodsWe included in patients undergoing renal biopsy at our facility and divided them into two groups: the WSI (-) group, underwent renal biopsy during (July, 2020-June, 2022), when WSI was not available, and the WSI (+) group (July, 2022-June, 2024), when WSI was available on electric medical record. The time from renal biopsy to the description of the pathological assessment, days to treatment initiation or modification, and the percentage of the assessment reported by nephrology trainees were compared between the two groups. Furthermore, this study included an inquiry about the usefulness of WSI from nephrologists who worked during these periods.

resultsThe time until assessment description and treatment initiation or modification were shorter in the WSI (+) group (p < 0.001 for both). Multivariable Cox regression analysis showed that the use of WSI had the most significant impact on these outcomes (p < 0.001). Moreover, the percentage of first assessments reported by nephrology trainees increased from 25.8% to 53.2% (p < 0.001), and multivariable logistic analysis showed that WSI was the most associated factor (p < 0.001). In the questionnaire, most nephrologists cited the ease of access and sharing as the main advantages of WSI.

conclusionsWSI is helpful for rapid treatment decision-making and education in renal pathology.

Indexed as

Clinical Decision-MakingKidneyKidney DiseasesNephrologyAdultAgedBiopsyFemaleHumansMaleMiddle AgedTime FactorsNephrology educationNephrology traineesRenal pathologyVirtual slideWhole slide imaging

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.