ArticleJournal of assisted reproduction and genetics2025
Every second counts: the association of embryo transfer duration with live birth following 2267 single, euploid, frozen embryo transfer.
Article in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Association of embryo transfer catheter maneuvers on clinical pregnancy and live birth.Journal of assisted reproduction and genetics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo identify the impact of the duration of the embryo transfer procedure on pregnancy outcomes.
methodsThis was a retrospective cohort study at a single center including single euploid frozen embryo transfers from April to December 2022. Embryo transfer time was defined as the total time (seconds) from when the embryologist handed the catheter with the loaded embryo to the physician, to the release of the embryo into the uterus. Time measurements were divided into quartiles: (1) 4-27 s, (2) 28-38 s, (3) 39-54 s, and (4) 55-1028 s. The primary outcome was the probability of live birth per transfer. Secondary outcomes included biochemical pregnancy, clinical pregnancy, and pregnancy loss.
resultsA total of 2267 frozen embryo transfer cycles were included in the analysis. The overall live birth rate was 59.8% (1356/2267). Compared to the fastest time (1st quartile), the probability of live birth was significantly decreased for couples with the longest transfer times (4th quartile) after adjusting for possible confounding variables (aOR, 0.76; 95% CI 0.58-0.99; p = 0.046). When patients with more difficult embryo transfers, that as a result may be inherently longer, were excluded, the results were the same as the primary model. However, when data was analyzed using only first transfers, compared to the shortest transfer time quartile (1st), there was a significant decreased probability of live birth in the 3rd quartile (OR 0.63, 95% CI 0.41-0.94, p = 0.025), but no significant differences in the 2nd or 4th quartile groups (p = 0.213, p = 0.800). There were no differences in the probability of biochemical pregnancy, clinical pregnancy, or pregnancy loss in the fully adjusted model.
conclusionThe longest embryo transfer times are associated with significantly decreased probability of live birth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.