Evidence map›Paper›PMID 40473900›Full record

ArticleProbiotics and antimicrobial proteins2026

Lactobacillus johnsonii JJB3 Ameliorates Oxidative Stress-Induced Intestinal Injury and Mitochondrial Damage by Promoting BNIP3L-Mediated Mitophagy.

Xingmei Liu, Jinge Xin, Ning Sun, Yuhua Qin, Haonan Huang, Benhao Chen, Lixiao Duan, Yanxi Zhou, Dandan Wang, Bo Jing and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xingmei Liu *Animal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Jinge Xin *Baiyun Branch, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Ning Sun *Animal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Yuhua Qin *College of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Haonan HuangAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Benhao ChenAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Lixiao DuanAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Yanxi ZhouAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Dandan WangAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Bo JingAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Yan ZengAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Dong ZengAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Kangcheng PanAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China.
Limin WeiChongqing Key Laboratory of High-Active Traditional Chinese Drug Delivery System, Chongqing Medical and Pharmaceutical College, Chongqing, China. pearl_0329@163.com.
Yu LinDepartment of Gastroenterology, Southern Medical University Hospital of Integrative Chinese and Western Medicine, Southern Medical University, Guangzhou, China. 13580311726@163.com.
Xueqin NiAnimal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China. xueqinni@foxmail.com.

Funding

National Natural Science Foundation 32270561President Foundation of Nanfang Hospital Baiyun Branch, Southern Medical University BYYZRC24001
6 · The paper itself

Abstract

The intestine is particularly susceptible to oxidative damage given its extensive exposure to environmental toxins, dietary components, and microbial metabolites, which leads to various gastrointestinal and systemic diseases. There is an urgent need for effective and safe therapies to maintain intestinal redox balance. This study aimed to explore whether the pig-native strain Lactobacillus johnsonii JJB3, known for its potential in mitigating oxidative stress, can prevent intestinal oxidative stress and elucidate its underlying mechanisms. Our study found that L. johnsonii JJB3 supernatant (sJJB3) effectively ameliorated hydrogen peroxide (H

Indexed as

Lactobacillus johnsoniiMembrane ProteinsMitochondriaMitophagyOxidative StressProbioticsAnimalsCell LineDiquatHydrogen PeroxideIntestinal MucosaIntestinesMaleMiceReactive Oxygen SpeciesSwineDiquatHydrogen PeroxideMembrane ProteinsReactive Oxygen SpeciesIntestinal injuryIntestinal microbiotaMitophagyOxidative stressProbiotics

Identifiers

PMID40473900

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.