Evidence map›Paper›PMID 40473888›Full record

Observational studyScientific reports2025

Comparison of safety and efficacy between double LVIS and flow diverter for Blister-Like aneurysms: a multicenter retrospective study.

Kai Chen, Wenshuai Li, Jingzheng Liu, Feng Guo, Zhen Xu, Chunhai Su, Haoran Qiu, Yang Yu, Jianfeng Zhuang, Maogui Li and 4 more

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kai ChenDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Wenshuai LiDepartment of Neurosurgery, Heze Municiple Hospital, Heze, China.
Jingzheng LiuDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Feng GuoDepartment of Neurosurgery, Linyi People's Hospital, Linyi, China.
Zhen XuDepartment of Neurosurgery, Jining First People's Hospital, Jining, China.
Chunhai SuDepartment of Neurosurgery, Jining First People's Hospital, Jining, China.
Haoran QiuDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Yang YuDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Jianfeng ZhuangDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Maogui LiDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Donghai WangDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Yunyan WangDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Wandong SuDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China.
Weiying ZhongDepartment of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, 107 West Culture Road, Shandong Province, China. zhongweiying123@163.com.

Funding

the Natural Science Foundation of Shandong Province ZR2022MH131
6 · The paper itself

Abstract

The aim of this study was to evaluate the efficacy and safety of using double overlapping LVIS and single Flow Diverter for the treatment of Blood Blister-like aneurysms (BBAs) in the internal carotid artery. In this retrospectively study, 88 patients with BBAs in the internal carotid artery who initially underwent treatment with either double LVIS or single Pipeline, with or without coiling, were recruited from four institutions between 2016 and 2023. Propensity score matching (PSM) analysis was utilized to balance the confounding factors. The overall rate of procedural complications was 17.0%, with favorable clinical outcomes observed in 89.8% of cases and complete IA occlusion achieved in 89.6% of cases. Procedure-related complications were found to be significant predictors of unfavorable clinical outcomes, while incomplete aneurysm occlusion on immediate angiography was a significant predictor of incomplete occlusion during follow-up (p<0.05). Double LVIS and single FD treatment, with or without coiling, demonstrated comparable rates of procedural complications, aneurysm occlusion, and favorable clinical outcomes at follow-up, both before and after propensity score matching (p>0.05). Double LVIS treatment with coiling was determined to be a safe, effective, and feasible alternative option for the treatment of BBAs.

Indexed as

Carotid Artery DiseasesCarotid Artery, InternalEmbolization, TherapeuticEndovascular ProceduresIntracranial AneurysmAdultAgedFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesTreatment OutcomeBlood Blister-like aneurysmComplicationEndovascular treatmentPrognosis

Identifiers

PMID40473888
PMCPMC12141509

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.