Evidence map›Paper›PMID 40473874›Full record

Observational studyHernia : the journal of hernias and abdominal wall surgery2025

How can we predict or prevent late mesh infection in ventral hernia repair? : Description of the type of study: a retrospective comparative study.

José Bueno-Lledó, Omar Carreño-Sáenz, Carla Perez-Alonso, Jesus Martinez-Hoed, Salvador Pous-Serrano

Abstract readComparative StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Mesh removal and ventral hernia repair with long-term absorbable mesh in case of mesh infection.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

José Bueno-LledóUnit of Abdominal Wall Surgery, Department of Digestive Surgery, Hospital Universitari i Politecnic "La Fe". University of Valencia, Calle Gabriel Miró 28, puerta 12, Valencia, 46008, Spain. buenolledo@hotmail.com.ORCID 0000-0002-3116-5022
Omar Carreño-SáenzUnit of Abdominal Wall Surgery, Department of Digestive Surgery, Hospital Universitari i Politecnic "La Fe". University of Valencia, Calle Gabriel Miró 28, puerta 12, Valencia, 46008, Spain.
Carla Perez-AlonsoUnit of Abdominal Wall Surgery, Department of Digestive Surgery, Hospital Universitari i Politecnic "La Fe". University of Valencia, Calle Gabriel Miró 28, puerta 12, Valencia, 46008, Spain.
Jesus Martinez-HoedUnit of Abdominal Wall Surgery. R. A. Calderón Guardia Hospital, San José, Costa Rica.
Salvador Pous-SerranoUnit of Abdominal Wall Surgery, Department of Digestive Surgery, Hospital Universitari i Politecnic "La Fe". University of Valencia, Calle Gabriel Miró 28, puerta 12, Valencia, 46008, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMesh infection (CMI) after ventral hernia repair (VHR) is uncommon, with an incidence of 1-7%. The aim of this observational retrospective study was (1) to analyse the incidence and aetiologies of late CMI (one or more years after prosthetic repair) in a series of VHR patients, (2) to identify pre-operative and perioperative variables related to late CMI and (3) to consider possible prevention measures to reduce its occurrence. MATERIALS AND

methodsA multivariate analysis of a prospective database of patients with a diagnosis of CMI who underwent open VHR between January 2014 and December 2023 at a tertiary centre was conducted. Institutional review board approval was obtained. Two groups of patients were compared: patients with onset of CMI less than one year after VHR (early CMI [ECMI] group) and patients with onset of CMI (sinus or suspected infection) one or more years after VHR (late CMI [LCMI] group).

resultsAt a median of 31.6 months (range: 19-55 months) of post-operative followup, 108 cases of CMI were reported, of which 64 cases were clinically diagnosed within one year of VHR (ECMI group) and 44 cases after one year (LCMI group). The most frequent clinical presentation of CMI was post-operative chronic sinus (94%) and mesh extrusion through the wound (6%). In multivariate analysis, pre-operative predictors associated with LCMI were BMI > 30 (p < 0.001; OR 1.980, p=0.002) and steroid or immunosuppressive drug use (p < 0.001; OR 1.06, p=0.004). Previous hernia repair using PTFE mesh was also a predictor of LCMI (p < 0.002; OR 2.11, p=0.000). Various factors, such as smoking, diabetes, previous hernia repair, presence of a stoma, operative time, concomitant enterotomy or post-operative SSI, were not significant indicators of LCMI.

conclusionsCMI is one of the most prevalent and challenging complications of VHR. Obesity (BMI > 30) and immunosuppression, as well as the use of ePTFE mesh in the previous hernia repair, are predictors of LCMI after VHR; studies of these factors may reduce and prevent the occurrence of LCMI.

Indexed as

Hernia, VentralHerniorrhaphyProsthesis-Related InfectionsSurgical MeshSurgical Wound InfectionAdultAgedFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesRisk FactorsTime FactorsAbdominal wall surgeryChronic mesh infectionLate mesh infectionPolypropilene meshPredictive factorsRisk factorsSurgical site occurrencesVentral hernia

Identifiers

PMID40473874

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.