Evidence map›Paper›PMID 40473727›Full record

ArticleScientific reports2025

miR-10-5p mediated susceptibility to chlorantraniliprole by targeting for SfGSTe1 in Spodoptera frugiperda (Smith).

Fan-Bin Kong, Ling-Ling Cui, Bai-Zhong Zhang, Yu-Tai Jiang, Yong-Po Lv, Pei Zhang, Yu-Yang Peng, Yun-Shan Xiong, Xiang Ji, Run-Qiang Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fan-Bin KongCollege of Resources and Environment, Henan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, 453003, China.
Ling-Ling CuiCollege of Resources and Environment, Henan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, 453003, China.
Bai-Zhong ZhangCollege of Resources and Environment, Henan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, 453003, China. baizhongok@163.com.
Yu-Tai JiangCollege of Resources and Environment, Henan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, 453003, China.
Yong-Po LvCollege of Resources and Environment, Henan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, 453003, China.
Pei ZhangCollege of Resources and Environment, Henan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, 453003, China.
Yu-Yang PengHebi Institute of Engineering and Technology, Henan Polytechnic University, Hebi, 458030, China.
Yun-Shan XiongHebi Institute of Engineering and Technology, Henan Polytechnic University, Hebi, 458030, China.
Xiang JiHebi Institute of Engineering and Technology, Henan Polytechnic University, Hebi, 458030, China.
Run-Qiang LiuCollege of Resources and Environment, Henan Engineering Research Center of Biological Pesticide & Fertilizer Development and Synergistic Application, Henan Institute of Science and Technology, Xinxiang, 453003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutathione S-transferases (GST) in pests plays a critical role in insecticide resistance. In this study, SfGSTe1 expression significant upregulation under chlorantraniliprole exposure, chlorantraniliprole susceptibility improvement after injected dsSfGSTe1 and miR-10-5p target located in the 3' UTR of SfGSTe1 conducted by luciferase reporter assays were observed in Spodoptera frugiperda (Smith). Injected miR-10-5p agomir reduced significantly SfGSTe1 abundance, together with increased chlorantraniliprole susceptibility, while injected miR-10-5p antagomir improved significantly SfGSTe1 abundance and thus decreased chlorantraniliprole susceptibility in the larvae of S. frugiperda. We revealed that the mRNA stability of SfGSTe1 by preventing its degradation that could have been induced by miR-10-5p and thus increased the resistance of S. frugiperda to chlorantraniliprole. This finding would help to study the mechanism of miRNAs in mediating insecticide susceptibility in pests.

Indexed as

Insecticide ResistanceInsecticidesInsect ProteinsMicroRNAsortho-AminobenzoatesSpodoptera3' Untranslated RegionsAnimalsGlutathione TransferaseLarva3' Untranslated RegionschlorantranilipoleGlutathione TransferaseInsecticidesInsect ProteinsMicroRNAsortho-AminobenzoatesChlorantraniliprole susceptibilitymiR-10-5pSfGSTe1Spodoptera frugiperda

Identifiers

PMID40473727
PMCPMC12141698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.