Evidence map›Paper›PMID 40473651›Full record

ArticleScientific reports2025

GCMS analysis and acaricidal activity of Ailanthus altissima extract against cattle tick Rhipicephalus (Boophilus) microplus and Hyalomma anatolicum: in vitro and in silico approach.

Shakir Ullah, Nosheen Malak, Afshan Khan, Sadaf Niaz, Raquel Cossío Bayúgar, Imtiaz Ahmad, Nasreen Nasreen, Nadia Bibi, Mourad Ben Said, Adil Khan and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shakir UllahDepartment of Zoology, Abdul Wali Khan University Mardan, Mardan, 23200, Pakistan.
Nosheen MalakDepartment of Zoology, Abdul Wali Khan University Mardan, Mardan, 23200, Pakistan.
Afshan KhanDepartment of Zoology, Abdul Wali Khan University Mardan, Mardan, 23200, Pakistan.
Sadaf NiazDepartment of Zoology, Abdul Wali Khan University Mardan, Mardan, 23200, Pakistan.
Raquel Cossío BayúgarInstituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias (INIFAP), Carretera Federal Cuernavaca-Cuautla No. 8534, Col. Progreso, C.P. 62550, Jiutepec, Morelos, Mexico.
Imtiaz AhmadDepartment of Botany, Bacha Khan University Charsadda, Charsadda, 24420, Pakistan.
Nasreen NasreenDepartment of Zoology, Abdul Wali Khan University Mardan, Mardan, 23200, Pakistan.
Nadia BibiDepartment of Microbiology, Shaheed Benazir Bhutto Women University (SBBWU), Peshawar, Pakistan.
Mourad Ben SaidLaboratory of Microbiology, National School of Veterinary Medicine of Sidi Thabet, University of Manouba, Manouba, Tunisia.
Adil KhanDepartment of Zoology, Bacha Khan University Charsadda, Charsadda, 24420, Pakistan. dradilkhan@bkuc.edu.pk.
Denekew TemesgenDepartment of Biology, Bahir Dar University, P.O. Box 79, Bahir Dar, Ethiopia. temesgenresearcher@gmail.com.
Most Nazmin AktarSchool of Natural Science, Macquarie University, Sydney, NSW, 2109, Australia.
Abdel-Rhman Z GaafarDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 11451, Riyadh, Saudi Arabia. agaafar@ksu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ticks, hematophagous ectoparasites, pose significant health risks to wildlife and humans as vectors for various pathogens. This study aims to assess the efficacy of Ailanthus altissima plant extract against Rhipicephalus (Boophilus) microplus and Hyalomma anatolicum ticks using both in vitro and in silico approaches. According to gas chromatography-mass spectrometry, 29 bioactive components with varying retention times have been identified in the methanol leaf extract of A. altissima. The plants methanolic extracts were prepared, subsequently diluted to concentrations of 25, 50, 75, and 100 mg/mL. Ticks underwent an adult immersion test (AIT) to evaluate extract effectiveness. AIT results were statistically analyzed via probit regression for lethal concentration (LC

Indexed as

AcaricidesAilanthusIxodidaePlant ExtractsRhipicephalusAcetylcholinesteraseAnimalsCattleComputer SimulationGas Chromatography-Mass SpectrometryGlutathione TransferaseMolecular Docking SimulationPlant LeavesAcaricidesAcetylcholinesteraseGlutathione TransferasePlant ExtractsAcaricidal activityAcetylcholine esteraseAilanthus altissimaGlutathione S transferaseHyalomma anatolicumPlant extractRhipicephalus (Boophilus) microplusTicks

Identifiers

PMID40473651
PMCPMC12141467

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.