Evidence map›Paper›PMID 40473458›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Feasibility of Short-Term Redifferentiation in Patients with Radioactive Iodine-Refractory Metastatic Thyroid Cancer.

Johannes von Hinten, Oliver Viering, Ralph A Bundschuh, Feyza Cagliyan, Hermann Wengenmair, Christian H Pfob, James Nagarajah, Constantin Lapa, Malte Kircher

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johannes von HintenNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Oliver VieringNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Ralph A BundschuhNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Feyza CagliyanNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Hermann WengenmairNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Christian H PfobNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
James NagarajahDepartment of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; and.
Constantin LapaNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany.
Malte KircherNuclear Medicine, Faculty of Medicine, University of Augsburg, Augsburg, Germany; malte.kircher@posteo.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioactive iodine-refractory thyroid cancer (TC) has a poor prognosis, and restoring iodine uptake is a major therapeutic goal. Recent studies have used tyrosine kinase inhibitors (TKIs) for 3-6 wk to achieve redifferentiation, but preclinical data suggest that maximal effects occur within 8-12 d.

Indexed as

Cell DifferentiationIodine RadioisotopesThyroid NeoplasmsAdultAgedFeasibility StudiesFemaleHumansImidazolesMaleMiddle AgedNeoplasm MetastasisOximesPilot ProjectsProtein Kinase InhibitorsPyridonesdabrafenibImidazolesIodine RadioisotopesOximesProtein Kinase InhibitorsPyridonesPyrimidinonestrametinibkinase inhibitionmetastatic differentiated thyroid carcinomaradioiodine-refractory thyroid cancerredifferentiation

Identifiers

PMID40473458
PMCPMC12320577

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.