Evidence map›Paper›PMID 40473411›Full record

ArticleMedical physics2025

Characterization of a shielded beam current transformer for ultra-high dose rate (FLASH) electron beam monitoring and dose reporting.

Thibault Bernelin, Bryan Muir, James Renaud, Karim Zerouali, Dominique Guillet, Louis Archambault, Arthur Lalonde

Abstract read
In one paragraph

Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thibault BernelinUniversité Laval, Québec, QC, Canada.
Bryan MuirMetrology Research Centre, National Research Council, Ottawa, ON, Canada.
James RenaudMetrology Research Centre, National Research Council, Ottawa, ON, Canada.
Karim ZeroualiCentre Hospitalier de l'Université de Montreal (CHUM), Montreal, QC, Canada.
Dominique GuilletCentre Hospitalier de l'Université de Montreal (CHUM), Montreal, QC, Canada.
Louis ArchambaultUniversité Laval, Québec, QC, Canada.
Arthur LalondeCentre de Recherche du Centre Hospitalier de l'Université de Montreal (CRCHUM), Montreal, QC, Canada.

Funding

Centre de Recherche du CHUMFonds de recherche du Québec 358165
6 · The paper itself

Abstract

backgroundReal-time beam monitoring and accurate dose reporting is challenging in ultra-high dose rate (UHDR) electron beams. Although beam current transformers (BCTs) can effectively track parameters such as pulse width (PW) and repetition frequency for UHDR electron beams, recent work has highlighted their sensitivity to electric fields induced by transient charge buildup in irradiated media under UHDR conditions. PURPOSE: This study evaluates the performance of a novel electrostatically shielded BCT for real-time, high-accuracy dose monitoring in UHDR electron beams.

methodsIrradiations were conducted using the Mobetron linear accelerator configured for UHDR electron beams with energies of 6 and 9 MeV. A shielded BCT was implemented to monitor beam delivery, with dose calibration established using alanine dosimeters in solid water phantoms. Dose stability was assessed over short (7-day) and long (16-week) periods. The BCT's response to variations in PW, pulse number, and pulse repetition frequency was also evaluated to determine its robustness across beam configurations.

resultsThe BCT showed high reproducibility and accuracy, with standard deviations of the difference between BCT-predicted and alanine-measured doses within 0.21% over short-term measurements and 0.57% over long-term measurements, even when subject to large (10%) machine output adjustments. When varying beam parameters, the BCT maintained accurate dose prediction within 1.0% and 1.4% of alanine measurements for 6 and 9 MeV, respectively, with high linearity (

conclusionShielded BCTs provide a stable and accurate solution for real-time dose monitoring in FLASH radiotherapy, demonstrating robustness against output fluctuations and beam parameter variations. While further calibration standardization is required, this study supports the feasibility of using shielded BCTs for reliable UHDR dose monitoring, facilitating safe and precise implementation of FLASH radiotherapy in preclinical and clinical settings.

Indexed as

ElectronsRadiation DosageRadiometryParticle AcceleratorsPhantoms, Imagingbeam current transformerelectron beamsFLASH radiotherapy

Identifiers

PMID40473411
PMCPMC12257996

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.