Evidence map›Paper›PMID 40473090›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2025

Prevalence and Impact of Social Risk in Patients With Inflammatory Bowel Diseases: National Estimates From the United States.

Elina Kim, Yuchen Qi, Matthew P Banegas, Michael D Kappelman, Nghia H Nguyen, Brigid S Boland, Carlos Lago Hernandez, Ronghui Xu, Siddharth Singh

Abstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elina KimDepartment of Medicine, University of California San Diego, La Jolla, California.
Yuchen QiBiostatistics and Bioinformatics, Herbert Wertheim School of Public Health, University of California San Diego, La Jolla, California.
Matthew P BanegasMoores Cancer Center at UC San Diego Health, La Jolla, California; Department of Radiation Medicine and Applied Sciences, School of Medicine, University of California San Diego, La Jolla, California.
Michael D KappelmanDivision of Pediatric Gastroenterology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Nghia H NguyenDivision of Gastroenterology, Kaiser Permanente Medical Center, Riverside, California.
Brigid S BolandDivision of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla, California.
Carlos Lago HernandezDivision of Hospital Medicine, Department of Medicine, University of California San Diego, La Jolla, California.
Ronghui XuBiostatistics and Bioinformatics, Herbert Wertheim School of Public Health, University of California San Diego, La Jolla, California; Department of Mathematics, University of California San Diego, La Jolla, California; Halicioglu Data Science Institute, University of California San Diego, La Jolla, California.
Siddharth SinghDivision of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla, California; Division of Biomedical Informatics, Department of Medicine, University of California San Diego, La Jolla, California. Electronic address: sis040@ucsd.edu.

Funding

San Diego Biomedical Informatics Education & Research (SABER)T15LM011271 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2012 to 2026
$9.7M
Comparative effectiveness research in Hispanic patients with inflammatory bowel diseasesR01DK135937 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Siddharth Singh · 2024 to 2026
$1.9M
NCCDPHP CDC HHS U01 DP006745NIDDK NIH HHS R01 DK135937NLM NIH HHS T15 LM011271
6 · The paper itself

Abstract

BACKGROUND &

aimsSocial risks are individual-level factors associated with adverse health outcomes. We determined the prevalence and impact of social risks on healthcare use among patients with inflammatory bowel diseases (IBDs) in the United States.

methodsIn the U.S. National Health Interview Survey 2023, we estimated social risks across 6 domains (food insecurity, financial hardship, housing instability, transportation needs, education and employment, discrimination) in adults with IBD. We evaluated the association between burden of social risk (0 of 6 domains [none], 1 of 6 domains [mild], 2 of 6 domains [moderate], and ≥3 of 6 domains [severe]), unplanned healthcare utilization (emergency department and/or hospitalization), and medication nonadherence, accounting for differences in age, sex, race/ethnicity, insurance, income, and comorbidities.

resultsOf 572 people included in the survey (mean age 56 years; 57% female; 81% non-Hispanic White [NHW], 12.9% Hispanic), 64% (95% confidence interval [CI], 59%-69%) experienced social risk across 1 or more domains (food insecurity, 22%; financial hardship, 28%; housing instability, 14%; transportation needs, 9%; education and employment, 9%; discrimination, 41%). Prevalence of severe social risk was higher in racial and ethnic minority groups (non-Hispanic Black vs Hispanic vs NHW: 37% vs 28% vs 12%). A higher burden of social risk was associated with higher risk of unplanned healthcare utilization (severe vs none: odds ratio, 3.5; 95% CI, 1.2-10.2) and cost-related medication nonadherence (OR, 11.8; 95% CI, 2.7-52.1), after accounting for income and insurance status.

conclusionsSocial risks are prevalent in adults with IBD and negatively impact healthcare utilization and medication nonadherence. Efforts to routinely identify and address social risks in patients with IBD should be part of standard clinical care.

Indexed as

Inflammatory Bowel DiseasesPatient Acceptance of Health CareAdultAgedFemaleFood InsecurityHumansMaleMiddle AgedPrevalenceRisk FactorsSocioeconomic FactorsUnited StatesYoung AdultCrohn’s DiseaseFinancial ToxicityHealth DisparitiesSocial Determinants of HealthUlcerative Colitis

Identifiers

PMID40473090
PMCPMC12354202

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.