Evidence map›Paper›PMID 40472782›Full record

ArticleJournal of the mechanical behavior of biomedical materials2025

3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms.

Shruthi Srinivasan, Kevin N Eckstein, Daniel Yoon, Ned C Rouze, Kaden D Bock, Estela Villacis, Philip V Bayly, Kathryn R Nightingale

Abstract read
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In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shruthi SrinivasanDepartment of Biomedical Engineering, Duke University, Durham, NC, United States. Electronic address: shruthi.srinivasan@duke.edu.
Kevin N EcksteinMechanical Engineering and Materials Science, Washington University, St. Louis, MO, United States.
Daniel YoonMechanical Engineering and Materials Science, Washington University, St. Louis, MO, United States.
Ned C RouzeDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Kaden D BockDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.
Estela VillacisMechanical Engineering and Materials Science, Washington University, St. Louis, MO, United States.
Philip V BaylyMechanical Engineering and Materials Science, Washington University, St. Louis, MO, United States.
Kathryn R NightingaleDepartment of Biomedical Engineering, Duke University, Durham, NC, United States.

Funding

3D Shearwave Elasticity Biomarker Development for Neuromuscular DiseaseR01EB033064 · NIBIB · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2022 to 2025
$2.3M
NIBIB NIH HHS R01 EB033064
6 · The paper itself

Abstract

We present ultrasonic 3D rotational shear wave elasticity imaging (3D-RSWEI) characterization of anisotropic 3D-printed hydrogel lattice phantoms that were originally developed for magnetic resonance elastography (MRE) applications. Shear wave speeds versus rotational angle were measured for two 3D-printed hydrogel lattices while submerged in water and after embedding in different stiffnesses of isotropic poly-vinyl alcohol (PVA). Shear wave propagation in the lattices was anisotropic, with faster wave speeds parallel to the scaling direction of the lattices. We observed that shear wave speeds and shear anisotropy decreased when the lattices were embedded in PVA versus submerged in water. Shear wave dispersion was observed in the lattice+PVA phantoms, with greater dispersion in the direction parallel to the scaling direction versus perpendicular. Dynamic shear testing results of the lattice+PVA phantoms were compared to 3D-RSWEI characterization with differences of 8.4% and 24.1% for propagation parallel and perpendicular to the scaling direction. These results demonstrate the feasibility of ultrasonic SWEI characterization of novel anisotropic MRE lattice phantoms.

Indexed as

Elasticity Imaging TechniquesImaging, Three-DimensionalPhantoms, ImagingAnisotropyPolyvinyl AlcoholPrinting, Three-DimensionalRotationPolyvinyl AlcoholAnisotropyCalibrating phantomsLattice structureMechanical testingShear wave elasticity imaging

Identifiers

PMID40472782
PMCPMC12259348

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.