Evidence map›Paper›PMID 40472110›Full record

ArticleScience (New York, N.Y.)2025

The complex role of brain cilia in feeding control.

Anushweta Asthana, Peter K Jackson

Abstract readComment
In one paragraph

Article in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Anushweta AsthanaBaxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Peter K JacksonBaxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.

Funding

Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5M
Training in Basic Research on Aging and Age-Related DiseaseT32AG000266 · NIA · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI Lisa M Ellerby · 1998 to 2026
$13.8M
Mechanisms of Ciliary Signaling Controlling Obesity and Metabolic DiseaseR01GM121565 · NIGMS · STANFORD UNIVERSITY · PI JACKSON, PETER KENT · 2017 to 2025
$4.3M
Fatty Acid Signaling via GPCRs in Primary Cilia Controls Adipogenesis and Insulin Secretion, Regulating Obesity and DiabetesR01DK127665 · NIDDK · STANFORD UNIVERSITY · PI JACKSON, PETER KENT, KIM, SEUNG K · 2021 to 2024
$2.0M
NIA NIH HHS T32 AG000266NIDDK NIH HHS P30 DK116074NIDDK NIH HHS R01 DK127665NIGMS NIH HHS R01 GM121565
6 · The paper itself

Abstract

Variants in a ciliary receptor are associated with obesity.

Indexed as

Appetite RegulationBrainCiliaObesityReceptors, G-Protein-CoupledAnimalsHumansMiceSmoothened ReceptorReceptors, G-Protein-CoupledSmoothened Receptor

Identifiers

PMID40472110
PMCPMC12998485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.