Evidence map›Paper›PMID 40472034›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Assembly of a functional neuronal circuit in embryos of an ancestral metazoan is influenced by temperature and the microbiome.

Christopher Noack, Sebastian Jenderny, Christoph Giez, Ornina Merza, Lisa-Marie Hofacker, Jörg Wittlieb, Urska Repnik, Marc Bramkamp, Karlheinz Ochs, Thomas C G Bosch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christopher NoackZoological Institute, University of Kiel, Kiel 24118, Germany.ORCID 0000-0003-2015-7147
Sebastian JendernyChair of Digital Communication Systems, Ruhr University Bochum, Bochum 44801, Germany.ORCID 0000-0001-9700-9295
Christoph GiezNeural Circuits and Evolution Laboratory, Francis Crick Institute, London NM1 1AT, UK.
Ornina MerzaZoological Institute, University of Kiel, Kiel 24118, Germany.ORCID 0009-0007-9709-8401
Lisa-Marie HofackerZoological Institute, University of Kiel, Kiel 24118, Germany.
Jörg WittliebZoological Institute, University of Kiel, Kiel 24118, Germany.
Urska RepnikCentral Microscopy Facility, University of Kiel, Kiel 24118, Germany.
Marc BramkampCentral Microscopy Facility, University of Kiel, Kiel 24118, Germany.ORCID 0000-0002-7704-3266
Karlheinz OchsChair of Digital Communication Systems, Ruhr University Bochum, Bochum 44801, Germany.
Thomas C G BoschZoological Institute, University of Kiel, Kiel 24118, Germany.ORCID 0000-0002-9488-5545

Funding

Canadian Institute for Advanced Research (ICRA) HMBDeutsche Forschungsgemeinschaft (DFG) CRC 1182 C1; CRC 1461 A1Deutsche Forschungsgemeinschaft (DFG) CRC 1461 A1
6 · The paper itself

Abstract

Understanding how neural populations emerge to give rise to behavior is a major goal in neuroscience. Here, we explore the self-assembly of neural circuits in

Indexed as

HydraMicrobiotaNerve NetNeuronsAnimalsBiological EvolutionEmbryo, NonmammalianGap JunctionsTemperatureartificial circuit modelingde novo nerve net assemblyenvironmental modulationmicrobiomeneural circuit development

Identifiers

PMID40472034
PMCPMC12168009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.