Observational studyPloS one2025
Upper extremity joint tenderness as a practical indicator for assessing presenteeism in rheumatoid arthritis patients: A cross-sectional observational study.
Observational study in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- DAS28-ESR may underestimate disease activity in rheumatoid arthritis patients with nonalcoholic fatty liver disease: a retrospective cohort study.Arthritis research & therapy · 2026Article
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveRheumatoid arthritis (RA) causes chronic polyarthritis and joint dysfunction, reducing work productivity. This reduction is mainly due to presenteeism, characterized by impaired work performance despite being present at work. This study aims to investigate the impact of specific joint involvement, particularly in the upper extremities, on work disability in RA patients.
methodsAnnual surveys assessing work disability were conducted among RA outpatients enrolled in the Nagahama Riumachi Cohort at Nagahama City Hospital, using the Work Productivity and Activity Impairment Questionnaire (WPAI). A multivariate regression analysis was performed to examine the cross-sectional and longitudinal associations between self-reported presenteeism and the tender joint count (TJC) in the extremities across two WPAI surveys.
resultsThe analysis included 201 patients, 52% of whom reported presenteeism. Cross-sectional analysis revealed a significant positive correlation between three or more TJCs of the upper extremity and presenteeism, with a regression coefficient (β) = 17.9 (95% confidence interval [CI]: 9.85-25.9). Among the joints evaluated, the sum of TJCs in the shoulder area (β = 9.55, CI: 5.39-13.7) and the fingers (β = 1.60, CI: 0.35-2.85) were significantly correlated with presenteeism. Additionally, change in presenteeism was significantly correlated with change in upper extremity TJCs (β = 1.41, CI: 0.05-2.77). No significant correlation was observed between lower extremity TJCs and presenteeism in these multivariate regression analyses.
conclusionsThe upper extremity TJC is strongly associated with presenteeism in RA patients. Minimizing TJC in the upper extremities, particularly in the shoulders and fingers, could be important treatment goal to reduce work disability in RA patients.
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