ReviewNeurochemical research2025
The Power of Neuroglia in Driving Brain Function.
Review in Neurochemical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The role of type I collagen in white matter injury.Anatomical science international · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Neuroglial cells are essential regulators of central nervous system (CNS) function in development, brain function, and disease. This mini-review summarizes recent advances that reveal how astrocytes, oligodendrocyte lineage cells, and microglia contribute to key brain processes. Astrocytes modulate synaptic plasticity and memory through gliotransmitter release, calcium signaling, and circuit-specific interactions, with dysfunctions implicated in disorders such as Alzheimer’s disease and depression. Oligodendrocytes and their precursors influence cognition through myelination, and disruptions in myelin plasticity and oligodendrogenesis can lead to significant cognitive deficits. Microglia, beyond their classical immune roles, are emerging as central sculptors of neural circuits, regulating synaptic pruning, neuronal survival, and extracellular matrix remodeling. Their dysfunction is increasingly associated with both neurodevelopmental and neurodegenerative disorders. Collectively, these findings highlight the powerful and multifaceted roles of neuroglial cells in shaping brain function and pathology. As tools to study and manipulate neuroglial activity continue to evolve, targeting neuroglial mechanisms offers exciting new therapeutic opportunities for a wide range of CNS disorders.
Indexed as
Identifiers
40471467What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.