Evidence map›Paper›PMID 40471455›Full record

ArticleInternational ophthalmology2025

Multifactorial analysis of dry eye syndrome: insights from Schirmer's test, VDT exposure, and tear film stability.

Sravani Mereddy, Ruchitha Priya Gunnam, Sai Ramya Karedla, Sourajit Kumar Banerjee, Suman Polaki

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Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Sravani MereddyDepartment of Optometry, School of Paramedical and Allied Health Sciences, Centurion University of Technology and Management, Vizianagaram, Andhra Pradesh, India. mereddysravani@gmail.com.
Ruchitha Priya GunnamDepartment of Optometry, School of Paramedical and Allied Health Sciences, Centurion University of Technology and Management, Vizianagaram, Andhra Pradesh, India.
Sai Ramya KaredlaDepartment of Optometry, School of Paramedical and Allied Health Sciences, Centurion University of Technology and Management, Vizianagaram, Andhra Pradesh, India.
Sourajit Kumar BanerjeeDepartment of Optometry, School of Paramedical and Allied Health Sciences, Centurion University of Technology and Management, Vizianagaram, Andhra Pradesh, India.
Suman PolakiDepartment of Biotechnology, M.S. Swaminathan School of Agriculture, Centurion University of Technology and Management, Parlakhemundi, Odisha, India. polaki.suman@cutm.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe current investigation represents to examine the numerous variables that influence tear film interactions alongside the seriousness regarding dry eye through adolescents and young adults, concentrating particularly regarding the implications of broadened Visual Display Terminal (VDT) usage, sleep deprivation, and the surrounding atmosphere. The inspection encompasses essential variables which include Schirmer's Test 1 (ST1), Tear Film Breakup Time (TBUT), ocular surface staining (OSS), tear osmolarity, blink rate, alongside symptom severity measured by the Ocular Surface Disease Index (OSDI).

methodsFifty participants (100 eyes; 33 males, 17 females), aged 18-25 years, were evaluated during morning and nocturnal phases following 5 h of VDT exposure. The purpose inspections comprised ST1, TBUT, OSS, tear osmolarity, alongside blink rate. The previously Ocular Surface Disease Index (OSDI) has been utilised for assessing unreliable warning signs. The statistical evaluations have been performed by employing paired t-tests, Pearson correlation, alongside straight-line regression mathematical modelling.

resultsST1 values decreased significantly at night (right eye: 18.06 ± 2.49 mm; left eye: 19.02 ± 2.48 mm) compared to morning (right eye: 22.18 ± 1.95 mm; left eye: 23.70 ± 1.94 mm) (p < 0.0001). TBUT declined from 7.2 ± 1.3 to 4.8 ± 1.6 s, accompanied by a 44% reduction in blink rate. OSDI scores rose from 25.4 ± 6.2 to 42.8 ± 7.9, correlating negatively with TBUT (r = -0.69, p < 0.01). Tear osmolarity demonstrated rising levels through ailments associated with lack of moisture alongside elevated the monitor luminescence. Significant correlations have been determined between ST1, TBUT, osmolarity, alongside OSS.

conclusionProlonged exposure to visual display terminals (VDT) alongside inadequate sleep considerably disrupt the tear film alongside intensify the signs of dry eye. Gender-related distinctions alongside the surrounding environment, moreover influences tear dynamics. The outcomes indicate an imperative of preventative screening, ergonomic interventions, along with customised techniques for management to reduce digital eye strain while maintaining ocular surface health in communities at high risk for injury.

Indexed as

Computer TerminalsDry Eye SyndromesTearsAdolescentAdultBlinkingFemaleHumansMaleOsmolar ConcentrationYoung AdultDry eye syndromeExposureOcular surface healthSchirmer’s testTear film breakup timeVisual display terminal

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.