ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025
Health-related quality of life trajectories in older adult long-term survivors of colorectal cancer.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeThe purpose of this study was to examine factors affecting health-related quality of life (HRQOL) over time in older adult survivors of colorectal cancer (CRC) and determine demographic and clinical characteristics associated with declines in HRQOL.
methodsThis secondary analysis utilized the Surveillance Epidemiology and End Results and Medicare Health Outcomes Survey and included CRC survivors aged 65 or older who completed at least one survey pre-diagnosis and two surveys within ten years post-diagnosis. HRQOL was captured by the Veterans Rand 12-item scale which provides mental and physical composite scores. Group-based trajectory modeling was employed to identify HRQOL trajectories. Multinomial logistic regression predicted group membership based on demographic and clinical characteristics.
resultsThe cohort (n = 649) was predominantly female (58%), white (70%), with an average age of 77 years. Most participants were diagnosed at Stage I disease (56%) and underwent surgery (63%). Three groups were identified based on trajectories of MCS: low increasing, medium decreasing, and high stable. Income and comorbidity number predicted MCS group membership. Five groups were identified based on trajectories of PCS: low decreasing, medium stable, steeply decreasing, high decreasing, and high stable. Older age at diagnosis, identifying as Hispanic, and comorbidity number predicted PCS group membership.
conclusionsComorbidities, age at diagnosis, ethnicity, and income significantly impact the HRQOL of older adult survivors of CRC. The resources and needs of each patient should be considered in long-term survivorship plans.
Indexed as
Identifiers
40471414What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.