Evidence map›Paper›PMID 40471412›Full record

ArticleJournal of molecular histology2025

Mitigation of cadmium-induced hepatotoxicity by orally administered Xylopia aethiopica synthesized silver nanoparticles in rats.

Emmanuel Nnaemeka Uhuo, Chiemeziem Adnma Obike, Parker Elijah Joshua, Prince Ogochukwu Alaebo, Rhonick Chukwuemeka Anyanwu

Abstract read
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In one paragraph

Article in Journal of molecular histology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emmanuel Nnaemeka UhuoDepartment of Biochemistry, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria. emmyuhuo@yahoo.com.
Chiemeziem Adnma ObikeDepartment of Biochemistry, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Parker Elijah JoshuaDepartments of Biochemistry, University of Nigeria Nsukka, Enugu, Enugu State, Nigeria.
Prince Ogochukwu AlaeboDepartment of Biochemistry, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Rhonick Chukwuemeka AnyanwuDepartment of Biochemistry, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium is a major environmental pollutant that results in hepatic necrosis by mediating oxidative stress and inflammation. Xylopia aethiopica is a natural plant that has been reported to have a wide range of pharmacological properties. The study aimed at determining the ameliorative potential of Xylopia aethiopica synthesized silver nanoparticles (Xa-AgNPs) against hepatotoxicity induced by cadmium in rats. Thirty male Wistar rats were randomly grouped into six (n = 5). I: served as control, II: received 10 mg/kg of silymarin only, III, IV, V, and VI were given 20 mg/kg b.wt of cadmium chloride (CdCl

Indexed as

CadmiumChemical and Drug Induced Liver InjuryMetal NanoparticlesSilverXylopiaAdministration, OralAnimalsAntioxidantsBiomarkersLiverMaleOxidative StressPlant ExtractsRatsRats, WistarAntioxidantsBiomarkersCadmiumPlant ExtractsSilverCadmiumHepatotoxicitySilver-nanoparticlesXylopia aethiopica

Identifiers

PMID40471412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.