Evidence map›Paper›PMID 40471411›Full record

ArticleOdontology2026

Gadolinium-doped hydroxyapatite coating on orthodontic miniscrews- an in-vitro analysis.

Priyadharshni Ramachandran, Shweta Nagesh, S P Mani, Revathi Peddu, Boyapati Ramanarayana

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Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Priyadharshni RamachandranDepartment of Orthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Shweta NageshDepartment of Orthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India. shwe14ta@gmail.com.ORCID http://orcid.org/0000-0002-1921-1604
S P ManiDepartment of Orthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Revathi PedduDepartment of Orthodontics, School of Dental Sciences, Sharda University, Greater Noida, India.
Boyapati RamanarayanaDepartment of Periodontology, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the efficacy of gadolinium-doped hydroxyapatite nanoparticles (Gd-HA Nps) as coating for orthodontic miniscrews. Gd-HA Nps were synthesized by sol-gel method and coated on titanium miniscrews utilizing dip coating. The coated screws were analyzed using Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), and Energy dispersive X-ray spectroscopy (EDS), confirming the effective application of the coating and the presence of 1.36 % Gd by weight. The antimicrobial effectiveness was evaluated using agar diffusion assays against Staphylococcus aureus (S. aureus) (p=0.029), Streptococcus mutans (S. mutans) (p=0.03), and Enterococcus faecalis (E. faecalis) (p=0.028). Gd-HA coated screws exhibited significantly larger zones of inhibition in comparison to pure HA-coated screws. The study indicates that Gd-HA coatings improve antibacterial capabilities, presenting a viable approach to mitigate peri-implant infections and failures.

Indexed as

Bone ScrewsCoated Materials, BiocompatibleDurapatiteGadoliniumOrthodontic Anchorage ProceduresAnti-Bacterial AgentsEnterococcus faecalisIn Vitro TechniquesMaterials TestingMicroscopy, Electron, ScanningNanoparticlesSpectrometry, X-Ray EmissionSpectroscopy, Fourier Transform InfraredStaphylococcus aureusStreptococcus mutansSurface PropertiesAnti-Bacterial AgentsCoated Materials, BiocompatibleDurapatiteGadoliniumTitaniumGadoliniumHydroxyapatiteImplantNanoparticlesOrthodontics

Identifiers

PMID40471411

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.