ArticleInternational ophthalmology2025
Comparison of Asian dust adhesion on the surface of different reusable silicone hydrogel contact lenses.
Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study aimed to compare the adhesion of Asian dust to four types of reusable silicone hydrogel soft contact lenses (SiHySCLs), including lehfilcon A, which was recently introduced in the market.
methodsFour types of SiHySCLs available in Japan (senofilcon A, samfilcon A, comfilcon A, lehfilcon A) were used (10 lenses per group). A 0.2 mL drop of phosphate-buffered saline (PBS) containing 0.01 mg/mL of Asian dust was randomly applied on the surface of the soft contact lens (SCL) using the Latin squares method. This was followed by 1 min of gentle agitation and 1 min of vibrational stirring after 1 h of static incubation. The lens was subsequently washed three times with PBS. The area of the Asian dust that had adhered after washing was quantified.
resultsThe proportion of residual particles adhering to the SiHySCL surface was as follows: senofilcon A (6.6 ± 1.3%), samfilcon A (0.6 ± 0.2%), comfilcon A (0.8 ± 0.4%), lehfilcon A (0.1 ± 0.1%). Compared to the other lenses, lehfilcon A exhibited significantly lower adhesion to Asian dust (all p < 0.01).
conclusionLehfilcon A demonstrated minimal adhesion of Asian dust components among the assessed reusable SiHySCLs, suggesting that it is a favorable option during periods of Asian dust exposure.
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