ArticleEuropean radiology2025
Novel insights into cardiac structure, function, perfusion, and tissue characteristics in liver cirrhosis: a magnetic resonance analysis.
Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Long-term cardiac remodeling after transjugular intrahepatic portosystemic shunt placement: a cardiac MRI study.European radiology · 2026Article
- Biventricular Systolic Function and Myocardial Deformation in Liver Cirrhosis: A Systematic Review and Meta-Analysis of Speckle-Tracking Echocardiography and Cardiac Magnetic Resonance Feature Tracking Studies.Journal of clinical medicine · 2026Review
- Magnetic resonance imaging-derived extracellular volume fraction mapping in metabolic dysfunction-associated steatotic liver disease reveals subclinical cardiac remodelling.Scientific reports · 2026Article
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Authors and funding
13 authors.
Funding
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Abstract
objectiveThis study analyzed the impact of liver cirrhosis on cardiac structure, function, tissue characteristics, and stress perfusion using cardiac magnetic resonance (CMR) imaging. MATERIALS AND
methodsFifty patients with liver cirrhosis and 25 matched, healthy controls received a 3-T CMR exam. Left and right ventricular (LV, RV) and atrial (LA, RA) volumes and functions were analyzed, including ejection fraction (EF), and feature tracking strain analysis. T1/T2 relaxation times and extracellular volume (ECV) were determined.
resultsPatients with cirrhosis showed a higher LVEF (66.6 ± 5.8 vs. 59.6 ± 4.5%, p < 0.001) and RVEF (65.4 ± 6.5 vs. 55.7 ± 8.0%, p < 0.001). LV (86.1 ± 16.2 vs. 78.0 ± 14 mL/m
conclusionLiver cirrhosis patients showed cardiac dilatation and increased ventricular function compared to controls. Non-ischemic LGE was present in 20% of patients. Disease severity scores were linked to an increased ECV and biventricular volumes. KEY POINTS: Question The effect of liver cirrhosis on cardiac structure, function, perfusion, and tissue characteristics has not been sufficiently investigated using cardiac MR. Findings Subjects with liver cirrhosis showed cardiac dilation, increased biventricular function compared to controls, non-ischemic LGE, and an association between disease severity and the extracellular volume. Clinical relevance Liver cirrhosis results in cardiac changes characterized by MR, predominantly dilatation and hypercontractility, as well as signs of myocardial fibrosis and elevated extracellular volume with increasing disease severity.
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