ArticleACS nano2025
Diffusion of DNA on Atomically Flat 2D Material Surfaces.
Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Chirality Engineering and Properties in Two-Dimensional Layered Materials.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Emission dipole orientation reveals dynamic single-molecule interactions with 2D crystals at solvent interfaces.Nature communications · 2026Article
- Modulation of Single-Molecule Emission at Hexagonal Boron Nitride Surfaces.Nano letters · 2026Article
- Actuation and Mapping of Surface Acoustic Wave Induced High-Frequency Wavefields on Suspended Graphene Membranes.ACS nano · 2025Article
- Monitoring Electrochemical Dynamics through Single-Molecule Imaging of hBN Surface Emitters in Organic Solvents.ACS nano · 2024Article
- Site-Specific Integration of Hexagonal Boron Nitride Quantum Emitters on 2D DNA Origami Nanopores.Nano letters · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate localization and delivery of biomolecules are pivotal for building tools to understand biology. The interactions of biomolecules with atomically flat 2D surfaces offer a means to realize both the localization and delivery, yet experimental utilization of such interactions has remained elusive. By combining single-molecule detection methods with computational approaches, we comprehensively characterize the interactions of individual DNA molecules with hexagonal boron nitride (hBN) surfaces. Our experiments directly show that, upon binding to a hBN surface, a DNA molecule retains its ability to diffuse along the surface. Further, we show that the magnitude and direction of such diffusion can be controlled by the DNA length, the surface topography, and atomic defects. We observe that the diffusion speed of the biomolecules is significantly lower than indicated by molecular dynamic simulations. Through computational analysis, we present the model based on temporary trapping by atomic defects that accounts for those observations. By fabricating a narrow hBN ribbon structure, we achieve pseudo-1D confinement, demonstrating its potential for nanofluidic guiding of biomolecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.