Evidence map›Paper›PMID 40471118›Full record

ArticleClinical implant dentistry and related research2025

Magnesium Resorbable Membrane for Guided Bone Regeneration in Critical Size Defect Model in Rabbits-Histomorphometric Analysis.

Ilan Beitlitum, Fatma Rayyan, Gil Slutzkey, Perry Raz, Rachel Sarig

Abstract read
In one paragraph

Article in Clinical implant dentistry and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ilan BeitlitumDepartment of Periodontology and Dental Implantology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Fatma RayyanDepartment of Periodontology and Dental Implantology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0009-0001-7802-1181
Gil SlutzkeyDepartment of Periodontology and Dental Implantology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-7244-4466
Perry RazDepartment of Periodontology and Dental Implantology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-1186-0546
Rachel SarigDepartment of Oral Biology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-9323-5014

Funding

The Siegmund and Lola Fischel Fund in Oral Implantology 33310000000
6 · The paper itself

Abstract

objectivesTo evaluate the effectiveness of a Mg-based membrane as a barrier for guided bone regeneration in rabbits calvaria. MATERIALS AND

methodsNine rabbits had four critical size defects created in each calvarium, randomly filled with a blood clot or bovine xenograft. One side was covered with the Mg-based membrane, and the control was left without membrane. After 8 weeks, histomorphometric analysis was performed to compare new bone formation with the pristine bone.

resultsMg-supported membrane for guided bone regeneration (GBR) is safe and promotes bone formation in critical size defects (CSD) in a rabbit calvaria. Gas accumulation was observed in a third of the specimens due to membrane degradation. Histomorphometric analysis revealed greater bone formation in the defects grafted with the Mg membrane (4.85 ± 1.73 mm

conclusionMg-based membrane supports guided bone regeneration (GBR), and when used in combination with a bone graft, enhances the performance despite the gas accumulation associated with membrane degradation. CLINICAL RELEVANCE: Limited data exist on the use of Mg-based membranes in GBR and its effect on bone formation.

Indexed as

Absorbable ImplantsBone RegenerationGuided Tissue RegenerationMagnesiumMembranes, ArtificialSkullAnimalsCattleRabbitsMagnesiumMembranes, Artificialcritical size defectsguided bone regenerationhistomorphometrymagnesiumrabbits calvaria modelresorbable membrane

Identifiers

PMID40471118
PMCPMC12139577

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.