Evidence map›Paper›PMID 40471061›Full record

ArticleIntegrative zoology2026

Mechanism of Ammonia-Induced Brain Damage in Chinese Striped-Necked Turtle (Mauremys sinensis).

Yunjuan Xiao, Xin Niu, Xueting Jiao, Liangping Lin, Haitao Shi, Meiling Hong, Li Ding

Abstract read
In one paragraph

Article in Integrative zoology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yunjuan XiaoMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China.
Xin NiuMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China.
Xueting JiaoMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China.
Liangping LinMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China.
Haitao ShiMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China.
Meiling HongMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China.
Li DingMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, China.

Funding

Hainan Province's Key Research and Development Project ZDYF2024SHFZ061National Natural Science Foundation of China 31960226National Natural Science Foundation of China 32160251National Natural Science Foundation of China 32271577
6 · The paper itself

Abstract

Social advancement and heightened waste discharge have resulted in escalating ammonia pollution in aquatic ecosystems, presenting toxicity hazards to aquatic fauna, especially turtles, by impairing their neurological function. To assess the ammonia effect on turtle brains, we subjected Chinese striped-necked turtles (Mauremys sinensis) to varying ammonia concentrations (CK, control; A1, 0.790 mg/L NH3; A2, 1.418 mg/L NH3) for durations of 24 and 48 h. Our data indicate that ammonia exposure markedly elevated glutamate levels and glutamate receptor mRNA expression in turtle brains, while concurrently diminishing glutamate transporter expression. These alterations resulted in an increase in brain water content, Na

Indexed as

AmmoniaBrainTurtlesWater Pollutants, ChemicalAnimalsGene Expression RegulationAmmoniaWater Pollutants, Chemicalammoniaapoptosiscalcium homeostasiscerebral edemaglutamateMauremys sinensis

Identifiers

PMID40471061
PMCPMC12971631

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.