Evidence map›Paper›PMID 40471058›Full record

ReviewPediatric pulmonology2025

Real-Time MRI of the Chest Wall, Diaphragm, and Lungs in Children.

Franz Wolfgang Hirsch, Ina Sorge, Christian Roth, Rebecca Anders, Jens Frahm, Dirk Voit, Freerk Prenzel, Martin Lacher, Daniel Gräfe

Abstract readReviewVideo-Audio Media
In one paragraph

Review in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Magnetic resonance imaging of the pediatric chest].Radiologie (Heidelberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Franz Wolfgang HirschDepartment of Pediatric Radiology, University Hospital Leipzig, Leipzig, Germany.ORCID https://orcid.org/0000-0003-0960-3740
Ina SorgeDepartment of Pediatric Radiology, University Hospital Leipzig, Leipzig, Germany.
Christian RothDepartment of Pediatric Radiology, University Hospital Leipzig, Leipzig, Germany.
Rebecca AndersDepartment of Pediatric Radiology, University Hospital Leipzig, Leipzig, Germany.
Jens FrahmBiomedical NMR, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.ORCID https://orcid.org/0000-0002-8279-884X
Dirk VoitBiomedical NMR, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.ORCID https://orcid.org/0000-0002-0058-2157
Freerk PrenzelDepartment of Pediatrics, University Hospital Leipzig, Leipzig, Germany.ORCID https://orcid.org/0000-0002-2838-593X
Martin LacherDepartment of Pediatric Surgery, University Hospital Leipzig, Leipzig, Germany.
Daniel GräfeDepartment of Pediatric Radiology, University Hospital Leipzig, Leipzig, Germany.ORCID https://orcid.org/0000-0002-7680-0990

Funding

This study was funded by European Society of Paediatric Radiology.
6 · The paper itself

Abstract

objectiveTo evaluate the clinical applicability and diagnostic potential of real-time magnetic resonance imaging (rtMRI) as a sedation-free, radiation-free imaging modality for assessing the chest wall, diaphragm, and lungs in children.

methodsThis video-based narrative review summarizes over four years of clinical experience with rtMRI in pediatric thoracic imaging. Real-time MRI achieves very high frame rates (up to 50 images per second), effectively minimizing motion artifacts. Representative clinical scenarios-including pneumonia, chest wall tumors, diaphragmatic dysfunction, airway anomalies, and congenital lung malformations-are presented to illustrate the diagnostic capabilities and limitations of rtMRI.

resultsReal-time MRI enables reliable imaging of thoracic structures in awake and uncooperative children, minimizing motion artifacts and thus eliminating the need for sedation. It provides diagnostic information on conditions such as pneumonia, abscesses, effusions, and neoplastic lesions, using two basic MR contrasts. Diaphragmatic motion and large airway morphology are clearly visualized. Limitations include reduced sensitivity for detecting interstitial lung disease and small pulmonary metastases. Complete thoracic examinations can be performed within 4 minutes, supporting rapid triage and potentially obviating the need for CT or sedated MRI in selected cases.

conclusionReal-time MRI is a promising, child-friendly alternative for thoracic imaging in pediatrics, particularly for evaluating chest wall abnormalities, diaphragmatic disorders, and pneumonia-related complications. Broader adoption and vendor-independent implementation may help establish rtMRI as a routine modality in pediatric chest imaging.

Indexed as

DiaphragmLungLung DiseasesMagnetic Resonance ImagingThoracic WallChildHumansmagnetic resonance imagingradiologyreal‐time imagingsedationthoracic imaging

Identifiers

PMID40471058
PMCPMC13020646

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.