Evidence map›Paper›PMID 40470936›Full record

ArticleMicrobiology spectrum2025

Gut microbiota regulates the brain metabolism of sexually mature drones.

Jun Zhang, Ya-Zhou Zhao, Meng-Shang Hou, Qi-He Tang, Yan-Tao Pang, Xi-Jie Li, Jian Xiong, Chong-Hui Zhao, Qi Huang, Shao-Jiang Tian and 3 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jun Zhang *Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.ORCID 0009-0002-9115-2378
Ya-Zhou Zhao *State Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.
Meng-Shang Hou *Sericulture and Apiculture Research Institute, Yunnan Academy of Agricultural Sciences, Mengzi, China.
Qi-He TangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Yan-Tao PangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Xi-Jie LiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Jian XiongYunnan Zhongfeng Technology Development Co. Ltd., Kunming, Yunnan, China.
Chong-Hui ZhaoFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Qi HuangKunming Maternity and Child Care Hospital, Kunming, Yunnan, China.
Shao-Jiang TianZhejiang Jiangshan Healthy Apiculture Co., Ltd., Jiangshan, Zhejiang, China.
Zhi-Xiang DongFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.ORCID 0009-0009-5426-0012
Zhen-Xing LiuState Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID 0000-0001-8236-1931
Jun GuoFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.ORCID 0000-0002-3612-8431

Funding

MOST | National Natural Science Foundation of China (NSFC) 32260863Yunnan Provincial Fundamental Research Projects CB22052C156A
6 · The paper itself

Abstract

Previous studies have found that gut microbiota and metabolites may be crucial in insect sexual maturation. For example, during sexual maturity, the increased dopamine in the drone's brain can affect its reproductive behavior, such as flight, mating, and so on. In addition, gut microbiota can affect brain functions such as learning and memory through metabolites. However, it is currently unclear about the changes in gut microbiota during drone sexual maturation and whether they can affect brain function through their metabolites. Thus, we analyzed gut microbiota and brain metabolome in drones during sexual maturation based on multi-omics and identified markers associated with sexual maturation. In addition, we also explored the potential correlation between differentially expressed microorganisms and metabolites before and after sexual maturation. The results showed significant changes in microbes (

Indexed as

BrainGastrointestinal MicrobiomeSexual MaturationAnimalsBacteriaMaleMetabolomebraindronegut microbiotametabolomicssexual maturation

Identifiers

PMID40470936
PMCPMC12210970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.