Evidence map›Paper›PMID 40470925›Full record

ArticleJournal of cardiovascular electrophysiology2025

Evidence of Late Septal Coronary Involvement After Bipolar Radiofrequency Ablation in a Patient With Lamin A/C Cardiomyopathy.

Alaa A Shalaby, Bassem S Hendawy, Daniel G Wann, Aditya Bhonsale, Krishna Kancharla, Andrew Voigt, Sandeep Jain, Mark Estes, Samir Saba, Konstantinos N Aronis

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In one paragraph

Article in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alaa A ShalabyDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-2000-7678
Bassem S HendawyDivisions of Transplantation, Hepatic and Renal Pathology/Thomas E. Starzl Institute University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Daniel G WannDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Aditya BhonsaleDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Krishna KancharlaDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Andrew VoigtDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Sandeep JainDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-5815-370X
Mark EstesDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-5461-7247
Samir SabaDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0003-4669-803X
Konstantinos N AronisDivision of Cardiac Electrophysiology, Heart and Vascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBipolar radiofrequency ablation has been increasingly used in cases with deep intramyocardial circuits refractory to unipolar ablation. Patients with Lamin A/C cardiomyopathy frequently exhibit VT arrhythmia originating from deep in the interventricular septum. METHODS AND

resultsWe describe our use of bipolar ablation in a patient with nonischemic cardiomyopathy and Lamin A/C mutation for the treatment of a septal VT substrate with particular attention to pathology findings at 3 months.

conclusionsBipolar ablation with catheters across the septum and in the presence of a microcatheter in a septal branch of the anterior interventricular vein was effective in controlling ventricular arrhythmia. Resultant ablation resulted in extensive myocardial injury and fibrosis. Neointimal hyperplasia of intervening coronary arteries may play a role in subsequent effects of initial ablation lesions.

Indexed as

CardiomyopathiesCatheter AblationCoronary VesselsLamin Type ATachycardia, VentricularHumansMaleMiddle AgedMutationTreatment OutcomeLamin Type ALMNA protein, humanbipolar ablationlamin A/C cardiomyopathyventricular tachycardia

Identifiers

PMID40470925
PMCPMC12337633

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.