Evidence map›Paper›PMID 40470871›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

In Situ Valence Engineering of Copper Silicate Nanozymes with Enhanced Peroxidase-Like Catalytic Activity for Oral Disease Detection.

Xiaocan Liu, Zhen Ding, Chengjing Xu, Jinming Zhang, Yufu Liu, Tianyan Chen, Shuang Dai, Xingfu Bao, Min Hu, Zhen Liu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaocan LiuJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Zhen DingJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Chengjing XuJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Jinming ZhangJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Yufu LiuJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Tianyan ChenJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Shuang DaiJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Xingfu BaoJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Min HuJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.
Zhen LiuJilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, 130021, China.ORCID https://orcid.org/0000-0002-1886-6457

Funding

Bethune Plan of Jilin University 2024B15Ethics Committee of School and Hospital of Stomatology of Jilin University SJDKQ2024004Fundamental Research Funds for Central Universities JLU-45124031C026Jilin Province Science and Technology Development Plan Project 20250601024RCMedicine+X" Interdisciplinary Innovation Project 2024JBGS07National Natural Science Foundation of China 22075011National Natural Science Foundation of China 22178140National Natural Science Foundation of China 82170994National Natural Science Foundation of China 82470987
6 · The paper itself

Abstract

As a series of attractive nanomaterials, nanozymes with great catalytic activity and specificity are well developed in the field of biosensors. Although promising, the lack of appropriate structural design strategy and limitation of sensing performance in the clinical samples remain challenging for the practical application of nanozymes. Herein, a novel copper silicate nanozyme (CSHSs-Ar) with enhanced peroxidase-like catalytic activity is synthesized through a facile in situ valence-engineered approach. After the optimization of synthesis, the resultant CSHSs-Ar nanozymes containing nearly 60% of Cu

Indexed as

Biosensing TechniquesCopperNanostructuresSilicatesCatalysisColorimetryHumansHydrogen PeroxidePeroxidaseCopperHydrogen PeroxidePeroxidaseSilicatesnanozymesperiodontitisperoxidase‐like catalytic activityvalence engineeringvolatile sulfur compounds (VSCs)

Identifiers

PMID40470871
PMCPMC12412579

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.