Evidence map›Paper›PMID 40470833›Full record

Trial reportSuicide & life-threatening behavior2025

The Family Check-Up and Youth Suicide: Assessing Indirect Effects of Improving Self-Regulation and Reducing Depression in Promoting Long-Term Resilience.

Samuel Seidman, Sarah Danzo, Arin Connell, Elizabeth Stormshak

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Suicide & life-threatening behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01490307 (A Family Intervention for Adolescent Problem Behavior), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01490307 nacompletednot on this map

A Family Intervention for Adolescent Problem Behavior

TypeinterventionalSponsorUniversity of OregonRan2006 to 2011Enrolled593ConditionsSubstance Use, Conduct Disorder, Depression, AnxietyArmsFamily Check-Up
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Annual Research Review: Beyond the target - understanding crossover effects in family-centered prevention.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Review
  2. Indirect Effects of the Coping Power Intervention on Latent Suicidal Thoughts and Behaviors: an Integrative Data Analysis.Prevention science : the official journal of the Society for Prevention Research · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samuel SeidmanColumbia University Irving Medical Center, New York City, New York, USA.ORCID https://orcid.org/0000-0001-6765-4867
Sarah DanzoUniversity of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0003-0637-7901
Arin ConnellCase Western Reserve University, Cleveland, Ohio, USA.
Elizabeth StormshakUniversity of Oregon, Eugene, Oregon, USA.

Funding

A Family Intervention for Adolescent Problem BehaviorR01DA018374 · NIDA · UNIVERSITY OF OREGON · PI STORMSHAK, ELIZABETH A · 2005 to 2009
$3.2M
Parenting to Prevent Substance Use in Late AdolescenceR01HD075150 · NICHD · UNIVERSITY OF OREGON · PI STORMSHAK, ELIZABETH A · 2012 to 2016
$3.0M
NICHD NIH HHS R01 HD075150NIDA NIH HHS DA018374NIDA NIH HHS HD075150NIDA NIH HHS R01 DA018374
6 · The paper itself

Abstract

objectiveThe Family Check-Up (FCU) is a family-focused prevention program originally developed to reduce externalizing behaviors, which has demonstrated improvements in internalizing behaviors and suicide. The present study attempted a conceptual replication of previous results from a separate trial of the FCU, initiated in early childhood, that found that the FCU predicts reductions in suicide risk via improvements in youth self-regulation.

methodsThe current study examined whether the FCU would predict reductions in youth suicidality via improvements in self-regulatory ability, in an independent trial of the FCU, initiated in early adolescence. The sample included 782 families, youth were 50.7% female, and 11 years old at baseline.

resultsFindings from previous trials were partially replicated, suggesting that improvements in self-regulatory skills in early adolescence support long-term reductions in suicide risk into early adulthood. However, the indirect effect of the FCU on suicide-related outcomes was only observed at the level of statistical trend in the current trial. Findings are discussed in the context of broader suicide treatments for youth involving family members and targeting important mechanisms of risk.

trial registrationNCT01490307.

Indexed as

DepressionFamilyFamily TherapyResilience, PsychologicalSelf-ControlSuicideSuicide PreventionAdolescentChildFemaleHumansMaleadolescencechildhoodfamily check upparentingpreventionsuicide

Identifiers

PMID40470833
PMCPMC12247049

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.