Evidence map›Paper›PMID 40470735›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Ferrocene-Functionalized Black Phosphorus Nanoplatform Enables Targeted and Prolonged MRI Visualization of Atherosclerotic Plaques.

Xiao Huang, Yuanyuan Zhao, Miao Zhou, Yukang Guo, Haiyun Wang, Yuanyuan Chen, Jian Peng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiao HuangInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Yuanyuan ZhaoInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Miao ZhouInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Yukang GuoInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Haiyun WangInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Yuanyuan ChenInstitute of Pharmaceutical Innovation, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, China.
Jian PengState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, China.ORCID https://orcid.org/0000-0002-2280-7214

Funding

7th Yong elite scientist sponsorship program by CAST YESS20210191Fundamental Research Funds for the Central Universities 2022IVA089Fundamental Research Funds for the Central Universities 2022IVA160Natural Science Foundation of China 21905237Natural Science Foundation of China 82302275Young Top-notch Talent Cultivation Program of Hubei Province 40129014
6 · The paper itself

Abstract

Despite the critical role of contrast-enhanced magnetic resonance imaging (MRI) in clinical diagnostics, current contrast agents face dual challenges: metallic formulations provoke biosafety concerns while organic radicals exhibit transient imaging windows. To overcome these limitations, a radical-engineered 2D black phosphorus (2D BP) nanoplatform is reported through atomic-scale conjugation of aminoferrocene, creating a stable complex with enhanced electron spin resonance, named FcP. The covalent coupling strategy establishes persistent T

Indexed as

Ferrous CompoundsMagnetic Resonance ImagingMetallocenesPhosphorusPlaque, AtheroscleroticAnimalsAtherosclerosisContrast MediaHumansHyaluronic AcidMiceContrast MediaferroceneFerrous CompoundsHyaluronic AcidMetallocenesPhosphorusatherosclerotic diagnosisblack phosphoruscontrast agentsmagnetic resonance imagingnon‐metallic agentsstable radical

Identifiers

PMID40470735
PMCPMC12407352

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.