Evidence map›Paper›PMID 40470714›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2025

Motor Performance, Health-Related Quality of Life and Self-Esteem in Early Adolescence After Neonatal Therapeutic Hypothermia.

Mimmi Eriksson Westblad, Sari Kokkonen Nassef, Mats Blennow, Maria Jirwe, Katarina Lindström

Abstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mimmi Eriksson WestbladDepartment of Clinical Science, Intervention and Technology, Division of Paediatrics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-6758-0535
Sari Kokkonen NassefDepartment of Clinical Science, Intervention and Technology, Division of Paediatrics, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-6828-7832
Mats BlennowDepartment of Clinical Science, Intervention and Technology, Division of Paediatrics, Karolinska Institutet, Stockholm, Sweden.
Maria JirweDepartment of Health Sciences, Swedish Red Cross University, Stockholm, Sweden.
Katarina LindströmDepartment of Clinical Science, Intervention and Technology, Division of Paediatrics, Karolinska Institutet, Stockholm, Sweden.

Funding

Anna-Lisa och Arne Gustafssons StiftelseCenter for Innovative Medicine H9641193Linnéa och Josef Carlssons StiftelseMajblommans RiksförbundNorrbacka-Eugeniastiftelsen 815/22Norrbacka-Eugeniastiftelsen 820/20Region Stockholm ALF 510097Stiftelsen Promobilia A22055Stiftelsen Promobilia A23011Stiftelsen SamaritenStiftelsen Sven Jerrings FondThe Queen Silvia Jubilee Foundation
6 · The paper itself

Abstract

aimTo explore the correlation between motor performance, health-related quality of life (HRQOL) and self-esteem in early adolescents treated with therapeutic hypothermia (TH) following neonatal hypoxic-ischaemic encephalopathy (HIE).

methodThis cross-sectional study included 45 children (mean age 11 years) with a neonatal TH-treated HIE between 2007 and 2009 in Stockholm. Motor performance was assessed with Movement Assessment Battery for Children-2 (MABC-2), HRQOL by Paediatric Quality of Life Inventory (PedsQL 4.0) and self-esteem with 'I Think I Am -2'. Nonparametric statistical methods were applied.

resultsSignificant positive correlations were found between MABC-2 scores and all PedsQL 4.0 dimensions in parents' reports (p < 0.001-0.029). Parents reported lower PedsQL 4.0 Total scores for children below the 15th percentile on MABC-2 (p = 0.004), while the self-reports of the same children were not significant (p = 0.098). Motor performance did not affect children's self-esteem; no difference was found between the group above or the group below the 15th percentile (p = 0.881).

conclusionDifferences between parent and child-reported outcomes suggest the need for continued follow-up of children treated with TH into adolescence, including HRQOL and self-esteem. Long-term assessment is necessary to identify challenges not captured in early childhood or by self-reports alone.

Indexed as

Hypothermia, InducedHypoxia-Ischemia, BrainMotor SkillsQuality of LifeSelf ConceptAdolescentChildCross-Sectional StudiesFemaleHumansInfant, NewbornMalehealth‐related quality of lifehypoxic–ischaemic encephalopathymotor performanceperinatal asphyxiaself‐esteemtherapeutic hypothermia

Identifiers

PMID40470714
PMCPMC12420856

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.