Evidence map›Paper›PMID 40470647›Full record

ArticleJournal of paediatrics and child health2025

Mycoplasma-Induced Rash and Mucositis: Ocular Manifestations, Treatment and Outcomes in a Paediatric Population.

Daniel Cool, Vivien Nguyen, Susan Zhang, Shiney Seo, Shuan Dai

Abstract read
In one paragraph

Article in Journal of paediatrics and child health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Mucositis Associated withChildren (Basel, Switzerland) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel CoolOphthalmology Department, Queensland Children's Hospital, Brisbane, Queensland, Australia.ORCID https://orcid.org/0009-0003-0338-4492
Vivien NguyenOphthalmology Department, Queensland Children's Hospital, Brisbane, Queensland, Australia.
Susan ZhangOphthalmology Department, Queensland Children's Hospital, Brisbane, Queensland, Australia.
Shiney SeoOphthalmology Department, Queensland Children's Hospital, Brisbane, Queensland, Australia.
Shuan DaiOphthalmology Department, Queensland Children's Hospital, Brisbane, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been an increase in Mycoplasma pneumoniae infections. This can present with extra-pulmonary manifestations including mycoplasma-induced rash and mucositis (MIRM). This paper aims to describe the ocular features in MIRM at a paediatric tertiary referral hospital in Queensland, Australia, and review the treatment and outcomes of these patients.

methodsA case series of 14 patients presenting to the Queensland Children's Hospital was included in this study. Patient demographics, ocular examination findings, and treatment methods were obtained from retrospective chart review.

resultsThe mean age was 11.2 years (range 8-15 years) and was mostly male (73%). All patients had conjunctival injection or ulceration. No patients had corneal involvement. One patient underwent amniotic membrane graft and glue tarsorrhaphy for one eye. All others were managed non-surgically with cautious use of topical steroid, as well as multidisciplinary care. Most patients (80%) achieved full recovery with no symblepharon formation or forniceal shortening.

conclusionConservative management with preservative-free antibiotics and lubricants should be considered as initial first-line treatment for patients presenting with MIRM. Topical corticosteroid therapy should be guided by an ophthalmology service. This should be in conjunction with systemic therapy and multidisciplinary care for extra-ocular complications. This case series suggests a treatment guideline for future patients presenting with possible MIRM. Paediatric and primary care physicians should be aware of ocular features of MIRM to facilitate early referral to and intervention by ophthalmologists to allow for the best outcome.

Indexed as

ExanthemaMucositisMycoplasma InfectionsAdolescentAnti-Bacterial AgentsChildFemaleHumansMaleQueenslandRetrospective StudiesTreatment OutcomeAnti-Bacterial Agentscommunitydermatologygeneral paediatricsimmunologyinfectious diseases

Identifiers

PMID40470647
PMCPMC12397835

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.