Evidence map›Paper›PMID 40470645›Full record

ArticleJournal of the American Heart Association2025

Extreme Heat and Arrhythmia in Patients With Implanted Devices.

Barrak Alahmad, Taofik Oyekunle, Claire Strohmeyer, Anderson P Rudke, Petros Koutrakis, Theofanie Mela

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Barrak AlahmadEnvironmental Health Department Harvard T.H. School of Public Health Boston MA.ORCID 0000-0002-9523-9537
Taofik OyekunleMedtronic, Clinical & Regulatory Solutions (MCRS) Medtronic Mounds View MN.
Claire StrohmeyerMedtronic, Clinical & Regulatory Solutions (MCRS) Medtronic Mounds View MN.
Anderson P RudkeDepartment of Sanitary and Environmental Engineering Federal University of Minas Gerais Belo Horizonte Brazil.ORCID 0000-0003-2970-5453
Petros KoutrakisEnvironmental Health Department Harvard T.H. School of Public Health Boston MA.
Theofanie MelaDepartment of Medicine and the Cardiac Arrhythmia Service, Massachusetts General Hospital Heart Center Harvard Medical School Boston MA.ORCID 0000-0002-7482-6214

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArrhythmia, particularly atrial fibrillation, is on the rise globally. While increased surveillance, aging populations, and other risk factors partially explain this rise, emerging risks such as extreme heat from climate change are underexplored.

methodsWe used Product Surveillance Registry by Medtronic (2016-2023) in the United States to examine patients with implantable cardioverter-defibrillator or cardiac resynchronization therapy defibrillator devices. We identified first arrhythmic episodes (atrial tachycardia/fibrillation [AT/AF] or ventricular tachycardia/fibrillation) recorded by devices. Events were matched to ambient temperatures from local weather stations. We used a case-crossover design where each arrhythmia event hour was matched with multiple control hours from the same patient, within the same day of week, month, and year. Conditional logistic models were then pooled across all climate zones in the United States to obtain nonlinear dose-response between temperature and arrhythmia.

resultsOur analysis included 3079 individuals across 103 cities. Fewer AT/AF and ventricular tachycardia/fibrillation events occurred during early morning hours (1 am-8 am) compared with daytime hours (9 am-4 pm) (

conclusionsExtreme hot outdoor temperatures were significantly associated with higher odds of AF episodes.

Indexed as

Arrhythmias, CardiacAtrial FibrillationDefibrillators, ImplantableExtreme HeatTachycardia, VentricularVentricular FibrillationAgedCross-Over StudiesFemaleHumansMaleMiddle AgedRegistriesRisk AssessmentRisk FactorsUnited Statesatrial fibrillationcardiac resynchronization therapy defibrillatorclimate changeenvironmentimplantable cardioverter‐defibrillatorventricular fibrillationventricular tachycardia

Identifiers

PMID40470645
PMCPMC12229103

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.