ReviewJournal of the American Heart Association2025
Exercise Prescription in Arrhythmogenic Cardiomyopathy: Finding the Right Balance Between Risks and Benefits.
Review in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Desmoplakin Loss Leads to PKC- and Src-Mediated Contractile Dysfunction in Cardiomyocytes.Circulation research · 2026Article
- Modeling the Exposome in Murine Cardiovascular Disease.JACC. Basic to translational science · 2026Review
- Borderline Arrhythmogenic Cardiomyopathy in an Athlete: Exercise Testing May Support Clinical Decision-Making.JACC. Case reports · 2026Article
- Precision Cardiogenomics in Athletes.International journal of molecular sciences · 2026Review
- Multi-site lactate kinetics during moderate intensity resistance and endurance exercise in definitive and probable arrhythmogenic cardiomyopathy.International journal of cardiology. Heart & vasculature · 2026Article
- Oxygen utilization during moderate-intensity resistance and aerobic exercise in arrhythmogenic cardiomyopathy: the central role of the periphery.ESC heart failure · 2026Article
- Arrhythmogenic Cardiomyopathy: Exercise and Divergent Phenotypes in a Family With a Pathogenic PKP2 Variant.JACC. Case reports · 2026Article
- Unveiling Arrhythmogenic Cardiomyopathy Masquerading as Myocarditis in a Professional Athlete.JACC. Case reports · 2026Article
- Physical activity and competitive sport safety for children affected by inherited cardiac conditions and selected acquired cardiomyopathies: emerging evidence and areas for further inquiry.European journal of pediatrics · 2026Review
- Drug-Resistant Sinus Tachycardia as a Dose-Dependent Side Effect of Spironolactone: A Case Report and Review of the Literature.Clinical case reports · 2026Article
- Exercise and competitive sport in those with genetic heart disease: what we know and what we don't know. Part 1.The British journal of cardiology · 2026Article
- Exercise Participation and Rehabilitation in Cardiomyopathies: An Updated Review.Journal of clinical medicine · 2025Review
- PANoptosis: a potential target of cardiomyopathy.Frontiers in immunology · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac condition, often caused by mutations in genes encoding desmosomal proteins. The pathologic hallmark of the disease is a fibrofatty replacement of the myocardium, which constitutes the substrate for potentially fatal ventricular arrhythmias. ACM is one of the most common etiology of sudden cardiac death in athletes and young individuals. Although it is well established that regular exercise confers multiple health benefits and better survival in the general population, intense exercise may accelerate the phenotypic expression and the propensity to ventricular arrhythmias in patients with ACM. This review discusses current evidence regarding the safety and the effects of exercise in ACM. We scrutinize research findings based on animal and human models that raise concerns on the possible detrimental role of intense exercise in this condition. Finally, we examine the current knowledge on exercise prescription focusing on the optimal amount of exercise that should be recommended to patients with ACM.
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