ArticleFrontiers in veterinary science2025
Relationship between plasma asprosin, dry matter intake, and plasma glucose at different stages of lactation.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In postpartum dairy cows, dry matter intake (DMI) decreases dramatically, resulting in reduced glucose production and negative energy balance (NEB). Asprosin is a centrally acting orexigenic protein hormone secreted by adipose tissue, and it promotes glucose production in the liver. However, the effects of asprosin on hepatic glucose output in primary bovine hepatocytes, as well as the relationship between plasma asprosin and dry matter intake at different stages of lactation, have not yet been reported. Our results demonstrated that fibrillin 1 (FBN1) exhibited significantly higher mRNA expression in the mammary gland and adipose tissue. The bovine His-asprosin proteins were > 90% pure, as confirmed by Coomassie Blue-stained SDS-PAGE gel analysis. Asprosin increased (
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